Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.55 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.55 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8587397 | 1.00 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2LMNAMAPTDPP8 | |
| Hydrochloric Acid SCHEMBL27949581 | 0.97 | LMNA (0.53) | ALDH1A1SMN1; SMN2LMNAMAPTDPP8 | |
| SCHEMBL9661798 | 0.88 | KCNJ1 (0.49) | ALDH1A1SMN1; SMN2LMNAMAPTDPP8 | |
| SCHEMBL9363980 | 0.87 | SMN1; SMN2 (0.52) | ALDH1A1SMN1; SMN2LMNAMAPTDPP8 | |
| SCHEMBL3039451 | 0.87 | KCNJ1 (0.53) | ALDH1A1SMN1; SMN2LMNAMAPTDPP8 | |
| SCHEMBL3039444 | 0.87 | SMN1; SMN2 (0.52) | ALDH1A1SMN1; SMN2LMNAMAPTDPP8 | |
| SCHEMBL10636452 | 0.87 | DPP8 (0.47) | ALDH1A1SMN1; SMN2LMNAMAPTDPP8 | |
| SCHEMBL8426254 | 0.87 | DPP8 (0.47) | ALDH1A1SMN1; SMN2LMNAMAPTDPP8 | |
| SCHEMBL5724018 | 0.86 | SMN1; SMN2 (0.51) | ALDH1A1SMN1; SMN2LMNAMAPTAKR1C3 | |
| Hydrochloric Acid SCHEMBL5724126 | 0.86 | KCNJ1 (0.52) | ALDH1A1SMN1; SMN2LMNAMAPTDPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0280771-B1 | 3-Pyrrolidinylthio-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid derivatives and processes for the preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-07-28 | — | — | EP | disclosed |
| US-5061804-A | 3-thiopyrrolidine as chemical intermediates | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-10-29 | — | — | US | disclosed |
| US-4963543-A | BACTERICIDES, TREATING INFECTIOUS DISEASES; THIENAMYCINS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-10-16 | — | — | US | disclosed |
| EP-0280771-A1 | 3-Pyrrolidinylthio-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid derivatives and processes for the preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-09-07 | — | — | EP | disclosed |