Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.73 |
| ▸ | NPC1 | O15118 | 6/20 | 0.73 |
| ▸ | MAPT | P10636 | 6/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.73 |
| ▸ | MEN1 | O00255 | 4/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.73 |
| ▸ | LMNA | P02545 | 3/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.73 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 2/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | MMP1 | P03956 | 3/20 | 0.46 |
| ▸ | MMP2 | P08253 | 3/20 | 0.46 |
| ▸ | MMP9 | P14780 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17664262 | 0.92 | ALDH1A1 (0.84) | RAB9AALDH1A1NPC1MAPTSMN1; SMN2 | |
| SCHEMBL19398197 | 0.89 | ALDH1A1 (0.79) | RAB9AALDH1A1NPC1MAPTSMN1; SMN2 | |
| SCHEMBL31501465 | 0.78 | EGFR (0.77) | MAPTMEN1KMT2AMAOAMAOB | |
| SCHEMBL546369 | 0.77 | RAB9A (0.83) | RAB9AALDH1A1NPC1MAPTSMN1; SMN2 | |
| SCHEMBL19403902 | 0.76 | HDAC1 (0.79) | RAB9AALDH1A1NPC1MAPTSMN1; SMN2 | |
| SCHEMBL27782898 | 0.76 | NPC1 (0.68) | RAB9AALDH1A1NPC1MAPTSMN1; SMN2 | |
| SCHEMBL27782907 | 0.76 | NPC1 (0.60) | RAB9AALDH1A1NPC1MAPTSMN1; SMN2 | |
| SCHEMBL11996395 | 0.74 | SMN1; SMN2 (0.68) | RAB9AALDH1A1NPC1MAPTSMN1; SMN2 | |
| SCHEMBL11996396 | 0.74 | SMN1; SMN2 (0.68) | RAB9AALDH1A1NPC1MAPTSMN1; SMN2 | |
| SCHEMBL10448340 | 0.73 | PRMT1 (0.66) | RAB9ANPC1MAPTSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103570723-A | Pyrazolopyrimidine derivative, its preparation method, and its use in preparation of medicines | UNIV SICHUAN | 2014-02-12 | — | — | CN | disclosed |