Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | S100A4 | P26447 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 3/20 | 0.42 |
| ▸ | PABPC1 | P11940 | 3/20 | 0.42 |
| ▸ | DNMT1 | P26358 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MPI | P34949 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7195529 | 0.88 | MAPK1 (0.44) | MEN1KMT2AMAPTMAPK1ALDH1A1 | |
| SCHEMBL15463120 | 0.86 | MEN1 (0.56) | MEN1KMT2AMAPTMAPK1ALDH1A1 | |
| SCHEMBL20888734 | 0.83 | MEN1 (0.49) | MEN1KMT2AMAPTMAPK1ALDH1A1 | |
| SCHEMBL18456446 | 0.82 | CDC25B (0.46) | MEN1KMT2AMAPTMAPK1ALDH1A1 | |
| SCHEMBL20889036 | 0.80 | MEN1 (0.46) | MEN1KMT2AMAPTMAPK1ALDH1A1 | |
| SCHEMBL19415805 | 0.80 | MEN1 (0.46) | MEN1KMT2AMAPTMAPK1ALDH1A1 | |
| SCHEMBL21871162 | 0.80 | MEN1 (0.49) | MEN1KMT2AMAPTMAPK1ALDH1A1 | |
| SCHEMBL12482939 | 0.80 | MEN1 (0.49) | MEN1KMT2AMAPTMAPK1ALDH1A1 | |
| SCHEMBL12483152 | 0.80 | MEN1 (0.49) | MEN1KMT2AMAPTMAPK1ALDH1A1 | |
| SCHEMBL20889035 | 0.80 | MEN1 (0.49) | MEN1KMT2AMAPTMAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11186545-B2 | Phenalene-1-one-containing photosensitizer composition, phenalene-1-one compound and the use thereof | TRIOPTOTEC GMBH (DE) | 2021-11-30 | — | — | US | disclosed |
| US-20200087259-A1 | PHENALENE-1-ONE-CONTAINING PHOTOSENSITIZER COMPOSITION, PHENALENE-1-ONE COMPOUND AND THE USE THEREOF | TRIOPTOTEC GMBH (DE) | 2020-03-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200087259-A1 | PHENALENE-1-ONE-CONTAINING PHOTOSENSITIZER COMPOSITION, PHENALENE-1-ONE COMPOUND AND THE USE THEREOF | PYCR1, CRY1, PPOX | MEN1 177/4885KMT2A 1375/4885MAPT 112/4885 |
| US-11186545-B2 | Phenalene-1-one-containing photosensitizer composition, phenalene-1-one compound and the use thereof | PYCR1, CRY1, PPOX | MEN1 177/4885KMT2A 1375/4885MAPT 112/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.