Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.35 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.34 |
| ▸ | IDO1 | P14902 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25524181 | 0.81 | RPS6KA5 (0.38) | RPS6KA5NTRK1 | |
| SCHEMBL27934679 | 0.79 | RPS6KA5 (0.35) | RPS6KA5NTRK1 | |
| SCHEMBL22308332 | 0.78 | LATS1 (0.38) | RPS6KA5 | |
| SCHEMBL15142332 | 0.78 | GRM8 (0.49) | NTRK1 | |
| SCHEMBL30996123 | 0.71 | NTRK1 (0.40) | RPS6KA5NTRK1 | |
| SCHEMBL14406911 | 0.71 | NTRK1 (0.44) | RPS6KA5NTRK1 | |
| SCHEMBL13627414 | 0.68 | HASPIN (0.46) | RPS6KA5NTRK1 | |
| SCHEMBL3656418 | 0.68 | HTR2A (0.62) | — | |
| SCHEMBL29611986 | 0.68 | HTR2A (0.62) | — | |
| SCHEMBL6982959 | 0.68 | HTR2A (0.62) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103664996-A | Indole derivative and preparation method thereof | INST MEDICINAL BIOTECHNOLOGY | 2014-03-26 | — | — | CN | disclosed |