Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 15/20 | 0.59 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27924049 | 0.91 | GRM2 (0.58) | GRM2ALOX5KCNH2 | |
| SCHEMBL758462 | 0.83 | GRM2 (0.70) | GRM2ALOX5KCNH2 | |
| SCHEMBL755743 | 0.81 | GRM2 (0.72) | GRM2ALOX5KCNH2 | |
| SCHEMBL755742 | 0.81 | GRM2 (0.72) | GRM2ALOX5KCNH2 | |
| SCHEMBL758425 | 0.79 | GRM2 (0.55) | GRM2ALOX5KCNH2 | |
| SCHEMBL2001260 | 0.75 | GRM2 (0.84) | GRM2ALOX5KCNH2 | |
| SCHEMBL756501 | 0.75 | GRM2 (0.84) | GRM2ALOX5KCNH2 | |
| SCHEMBL757567 | 0.75 | GRM2 (1.00) | GRM2ALOX5KCNH2 | |
| SCHEMBL757568 | 0.75 | GRM2 (1.00) | GRM2ALOX5KCNH2 | |
| SCHEMBL756231 | 0.74 | GRM2 (0.83) | GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101657443-B | [1,2,3] triazole-substituted quinolines and coumarins as leukotriene biosynthesis inhibitors | MERCK FROSST CANADA LTD | 2013-10-23 | — | — | CN | disclosed |