Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.53 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.53 |
| ▸ | IDO1 | P14902 | 1/20 | 0.53 |
| ▸ | CASP1 | P29466 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2597823 | 0.82 | HIF1A (0.61) | HIF1AHPGDALOX15MEN1CYP3A4 | |
| SCHEMBL20656766 | 0.76 | ALOX15 (0.63) | HIF1AHPGDALOX15MEN1CYP3A4 | |
| SCHEMBL2835839 | 0.74 | CDK4 (0.47) | HIF1AHSPA5IDO1HSD17B10AKR1B1 | |
| SCHEMBL28074487 | 0.74 | HPGD (0.61) | HIF1AHPGDALOX15MEN1CYP3A4 | |
| SCHEMBL2490536 | 0.74 | GABRA1 (0.66) | HIF1AHPGDALOX15MEN1CYP3A4 | |
| SCHEMBL24074915 | 0.73 | MEN1 (0.54) | HIF1AHPGDALOX15MEN1CYP3A4 | |
| SCHEMBL27584739 | 0.73 | MEN1 (0.54) | HIF1AHPGDALOX15MEN1CYP3A4 | |
| SCHEMBL10908436 | 0.71 | HTT (0.60) | HIF1AHPGDALOX15MEN1CYP3A4 | |
| SCHEMBL7519481 | 0.71 | ALOX15 (0.57) | HIF1AHPGDALOX15MEN1CYP3A4 | |
| SCHEMBL622778 | 0.71 | HPGD (0.68) | HIF1AHPGDALOX15MEN1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103382196-A | (E)-1-(8-benzopyranyl)-2-allyl-1-one and its analogues, and use thereof | UNIV SICHUAN | 2013-11-06 | — | — | CN | disclosed |