Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 7/20 | 0.63 |
| ▸ | PTGES2 | Q9H7Z7 | 8/20 | 0.55 |
| ▸ | ACLY | P53396 | 2/20 | 0.49 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28808565 | 0.83 | CCR2 (0.61) | CCR2SLC40A1MCL1 | |
| SCHEMBL28076112 | 0.80 | CCR2 (0.64) | CCR2ACLYSLC40A1 | |
| SCHEMBL9933923 | 0.78 | CCR2 (1.00) | CCR2PTGES2ACLYSLC40A1 | |
| SCHEMBL9934413 | 0.76 | CCR2 (1.00) | CCR2PTGES2ACLYSLC40A1 | |
| SCHEMBL9935336 | 0.74 | CCR2 (0.70) | CCR2PTGES2ACLYSLC40A1MCL1 | |
| SCHEMBL27943889 | 0.73 | CCR2 (0.60) | CCR2MCL1 | |
| SCHEMBL27943738 | 0.73 | CCR2 (0.59) | CCR2 | |
| SCHEMBL28289868 | 0.72 | CCR2 (0.78) | CCR2PTGES2 | |
| SCHEMBL3782531 | 0.71 | PTGES2 (1.00) | CCR2PTGES2ACLYSLC40A1 | |
| SCHEMBL28871800 | 0.71 | CCR2 (0.79) | CCR2PTGES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103380115-A | Sulfur derivatives as chemokine receptor modulators | ALLERGAN INC | 2013-10-30 | — | — | CN | claimed |
| CN-103380115-A | Sulfur derivatives as chemokine receptor modulators | ALLERGAN INC | 2013-10-30 | — | — | CN | disclosed |