Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 16/20 | 0.64 |
| ▸ | SLC40A1 | Q9NP59 | 2/20 | 0.46 |
| ▸ | ACLY | P53396 | 1/20 | 0.44 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28808565 | 0.94 | CCR2 (0.61) | CCR2SLC40A1 | |
| SCHEMBL27943751 | 0.80 | CCR2 (0.63) | CCR2SLC40A1ACLY | |
| SCHEMBL9933360 | 0.78 | CCR2 (1.00) | CCR2 | |
| SCHEMBL21442611 | 0.75 | CCR2 (0.63) | CCR2ACLYPIK3CD | |
| SCHEMBL9934423 | 0.75 | CCR2 (0.88) | CCR2 | |
| SCHEMBL3748809 | 0.75 | CCR2 (0.67) | CCR2ACLY | |
| SCHEMBL9934374 | 0.74 | CCR2 (0.69) | CCR2SLC40A1ACLYPIK3CD | |
| SCHEMBL27943738 | 0.73 | CCR2 (0.59) | CCR2 | |
| SCHEMBL7572525 | 0.73 | CCR2 (0.63) | CCR2 | |
| SCHEMBL3743872 | 0.72 | CCR2 (0.66) | CCR2ACLY |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103380115-B | Sulfur derivatives as chemokine receptor modulators | 阿勒根公司 | 2016-08-24 | — | — | CN | claimed |
| CN-106220618-B | Sulfur derivatives as chemokine receptor modulators | 阿勒根公司 | 2019-04-26 | — | — | CN | disclosed |
| CN-106220618-A | SULFUR DERIVATIVES AS CHEMOKINE RECEPTOR MODULATORS | 阿勒根公司 | 2016-12-14 | — | — | CN | disclosed |
| CN-103380115-B | Sulfur derivatives as chemokine receptor modulators | 阿勒根公司 | 2016-08-24 | — | — | CN | disclosed |