Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SYK | P43405 | 7/20 | 0.38 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.38 |
| ▸ | INCENP | Q9NQS7 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.36 |
| ▸ | KDM5C | P41229 | 3/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.36 |
| ▸ | KDM4A | O75164 | 2/20 | 0.35 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.35 |
| ▸ | KDM4B | O94953 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6637823 | 0.84 | TSHR (0.47) | TSHRKDM4ELMNACYP3A4CYP1A2 | |
| SCHEMBL24690842 | 0.80 | PKM (0.46) | TSHRKDM4ELMNACYP3A4CYP1A2 | |
| SCHEMBL18415056 | 0.80 | CYP1A2 (0.61) | TSHRKDM4ELMNACYP3A4CYP1A2 | |
| SCHEMBL12640033 | 0.79 | CYP1A2 (0.42) | TSHRKDM4ELMNACYP3A4CYP1A2 | |
| SCHEMBL12734425 | 0.76 | SYK (0.44) | TSHRKDM4ELMNACYP3A4CYP1A2 | |
| SCHEMBL12640104 | 0.76 | MEN1 (0.46) | TSHRKDM4ELMNACYP3A4CYP1A2 | |
| SCHEMBL22214937 | 0.76 | TSHR (0.45) | TSHRKDM4ELMNACYP3A4CYP1A2 | |
| SCHEMBL6643292 | 0.75 | TSHR (0.40) | TSHRKDM4ELMNACYP3A4CYP1A2 | |
| SCHEMBL28298258 | 0.75 | CYP1A2 (0.39) | TSHRKDM4ELMNACYP3A4CYP1A2 | |
| SCHEMBL19676370 | 0.72 | KDM5B (0.50) | TSHRKDM4ELMNACYP3A4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103638533-B | A kind of preparation method of the hypotoxic magnetic Nano rod of targeting HIF | 江苏大学 | 2016-06-15 | — | — | CN | claimed |
| CN-103638533-A | Preparation method of magnetic nanorod with targeted HIF (hypoxia inducible factor) low toxicity | UNIV JIANGSU | 2014-03-19 | — | — | CN | claimed |
| CN-103638533-B | A kind of preparation method of the hypotoxic magnetic Nano rod of targeting HIF | 江苏大学 | 2016-06-15 | — | — | CN | disclosed |
| CN-103638533-B | A kind of preparation method of the hypotoxic magnetic Nano rod of targeting HIF | 江苏大学 | 2016-06-15 | — | — | CN | disclosed |
| CN-103638533-A | Preparation method of magnetic nanorod with targeted HIF (hypoxia inducible factor) low toxicity | UNIV JIANGSU | 2014-03-19 | — | — | CN | disclosed |