Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 1/20 | 0.61 |
| ▸ | FNTB | P49356 | 1/20 | 0.61 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.61 |
| ▸ | PKM | P14618 | 14/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tomenphantin A SCHEMBL6484758 | 1.00 | FNTA (0.61) | FNTAFNTBPGGT1BPKMKDM4E | |
| Tomenphantin A SCHEMBL30039069 | 1.00 | FNTA (0.61) | FNTAFNTBPGGT1BPKMKDM4E | |
| SCHEMBL28254414 | 0.79 | FNTA (0.92) | FNTAFNTBPGGT1BPKMKDM4E | |
| Elephantopin SCHEMBL8401219 | 0.76 | GPX4 (0.62) | FNTAFNTBPGGT1BPKMKDM4E | |
| Elephantopin SCHEMBL30350210 | 0.76 | GPX4 (0.62) | FNTAFNTBPGGT1BPKMKDM4E | |
| Melampomagnolide B SCHEMBL16706262 | 0.75 | PKM (1.00) | PKMNPC1MAPTHTTRAB9A | |
| Melampomagnolide B SCHEMBL30081323 | 0.75 | PKM (1.00) | PKMNPC1MAPTHTTRAB9A | |
| Melampomagnolide B SCHEMBL16229963 | 0.75 | PKM (1.00) | PKMNPC1MAPTHTTRAB9A | |
| Melampomagnolide B SCHEMBL16922753 | 0.75 | PKM (1.00) | PKMNPC1MAPTHTTRAB9A | |
| Melampomagnolide B SCHEMBL4761798 | 0.75 | PKM (1.00) | PKMNPC1MAPTHTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103408562-A | Preparation method of elephantopin A | NANJING ZELANG MEDICAL TECH CO | 2013-11-27 | — | — | CN | disclosed |