Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FASN | P49327 | 1/20 | 0.48 |
| ▸ | CCNC | P24863 | 1/20 | 0.42 |
| ▸ | CDK8 | P49336 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 7/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.39 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | PLK4 | O00444 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27774785 | 0.90 | SLC6A2 (0.44) | FASNCCNCCDK8SLC6A2SLC6A4 | |
| SCHEMBL9952336 | 0.83 | FASN (0.52) | FASNROCK2CYP3A4PIK3CD | |
| SCHEMBL27665777 | 0.81 | CYP3A4 (0.57) | CDK8SLC6A2SLC6A4SLC6A3ROCK2 | |
| SCHEMBL15556237 | 0.78 | FASN (0.55) | FASNCCNCCDK8ROCK2CYP3A4 | |
| SCHEMBL9917339 | 0.78 | SLC6A2 (0.55) | FASNSLC6A2SLC6A4SLC6A3ROCK2 | |
| SCHEMBL27926231 | 0.76 | TLR7 (0.36) | CCNCCDK8 | |
| SCHEMBL3328409 | 0.76 | PIK3CD (0.49) | FASNCCNCCDK8SLC6A2SLC6A4 | |
| SCHEMBL4833473 | 0.75 | ROCK2 (0.52) | FASNSLC6A2SLC6A4SLC6A3ROCK2 | |
| SCHEMBL27984917 | 0.75 | HSD11B1 (0.46) | ROCK2HSD11B1 | |
| SCHEMBL27792727 | 0.74 | CYP3A4 (0.47) | ROCK2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103429585-A | Indazolyl triazole derivatives as interleukin-1 receptor associated kinase inhibitors | MERCK SERONO SA | 2013-12-04 | — | — | CN | disclosed |