Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.47 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ELANE | P08246 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27673919 | 0.95 | ATM (0.48) | HPGDRAB9ASMN1; SMN2GAAHTT | |
| SCHEMBL27677506 | 0.83 | KMT2A (0.45) | GAALMNA | |
| SCHEMBL27947005 | 0.77 | KMT2A (0.43) | — | |
| SCHEMBL4266412 | 0.75 | KCNK3 (0.61) | HPGDRAB9ASMN1; SMN2GAAHTT | |
| SCHEMBL33443 | 0.75 | SRD5A2 (0.67) | HPGDRAB9AKCNK3KCNK9POLB | |
| SCHEMBL1427963 | 0.75 | SRD5A2 (0.67) | HPGDRAB9AKCNK3KCNK9POLB | |
| SCHEMBL15155929 | 0.75 | SRD5A2 (0.67) | HPGDRAB9AKCNK3KCNK9POLB | |
| Bicarbonate SCHEMBL6612782 | 0.73 | SRD5A2 (0.65) | HPGDRAB9AKCNK3KCNK9POLB | |
| SCHEMBL965420 | 0.72 | SRD5A2 (0.63) | HPGDPOLBELANE | |
| SCHEMBL28535957 | 0.72 | RAB9A (0.56) | HPGDRAB9ASMN1; SMN2GAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103384672-A | N-substituted oxazinopteridines and oxazinopteridinones | TAKAEDA CHEMICAL IND LTD | 2013-11-06 | — | — | CN | disclosed |