Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCAT2 | O15382 | 2/20 | 0.45 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.37 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.36 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.36 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.36 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19812980 | 0.77 | MAPK1 (0.48) | BCAT2GRM4 | |
| SCHEMBL4088660 | 0.76 | KMT2A (0.44) | CYP11B2CYP11B1MAP3K14SMN1; SMN2NPC1 | |
| SCHEMBL16914120 | 0.71 | HSD17B10 (0.49) | L3MBTL1CYP11B2NPC1HTTHPGD | |
| SCHEMBL123331 | 0.69 | BCAT2 (0.45) | BCAT2TDP1GRM1NPC1RAB9A | |
| SCHEMBL23356622 | 0.69 | KMT2A (0.55) | BCAT2TDP1GRM1SMN1; SMN2NPC1 | |
| SCHEMBL29458437 | 0.69 | KMT2A (0.55) | BCAT2TDP1GRM1SMN1; SMN2NPC1 | |
| SCHEMBL29163638 | 0.69 | CRBN (0.56) | BCAT2GRM4GRIN2DGRIN3BGRIN1 | |
| SCHEMBL798870 | 0.68 | CYP11B2 (0.47) | BCAT2GRM4TDP1CYP11B2CYP11B1 | |
| SCHEMBL29923615 | 0.68 | CYP11B2 (0.50) | BCAT2CYP11B2CYP11B1 | |
| SCHEMBL2600444 | 0.68 | NPC1 (0.68) | BCAT2CYP11B2CYP11B1AOC3SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103429582-A | MST1 kinase inhibitors and method of use thereof | LEXICON PHARMACEUTICALS INC | 2013-12-04 | — | — | CN | disclosed |