Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.55 |
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | NPC1 | O15118 | 9/20 | 0.51 |
| ▸ | RAB9A | P51151 | 9/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.49 |
| ▸ | RELA | Q04206 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | APEX1 | P27695 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | SNCA | P37840 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30739965 | 0.88 | LMNA (0.71) | MEN1KMT2ATDP1SMN1; SMN2LMNA | |
| SCHEMBL94664 | 0.85 | MEN1 (0.58) | MEN1KMT2ATDP1SMN1; SMN2LMNA | |
| SCHEMBL1826301 | 0.84 | MEN1 (0.62) | MEN1KMT2ATDP1SMN1; SMN2LMNA | |
| SCHEMBL679040 | 0.84 | MEN1 (0.83) | MEN1KMT2ATDP1SMN1; SMN2LMNA | |
| SCHEMBL7331132 | 0.84 | MEN1 (0.57) | MEN1KMT2ATDP1SMN1; SMN2LMNA | |
| SCHEMBL27928793 | 0.79 | MEN1 (0.55) | MEN1KMT2ATDP1SMN1; SMN2LMNA | |
| SCHEMBL678422 | 0.79 | JAK2 (0.65) | MEN1KMT2ATDP1SMN1; SMN2LMNA | |
| SCHEMBL8402954 | 0.78 | KMT2A (0.64) | MEN1KMT2ATDP1SMN1; SMN2LMNA | |
| SCHEMBL679010 | 0.78 | HPGD (0.74) | MEN1KMT2ATDP1SMN1; SMN2LMNA | |
| SCHEMBL17063932 | 0.77 | P2RX7 (0.50) | MEN1KMT2ATDP1SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101952287-B | Protein kinase inhibitors and use thereof | MERCK SERONO SA | 2013-11-27 | — | — | CN | disclosed |