Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.38 |
| ▸ | BUB1 | O43683 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27929320 | 0.89 | LMNA (0.43) | NR1H4NPC1RAB9AL3MBTL1SMN1; SMN2 | |
| SCHEMBL27946642 | 0.87 | PDE5A (0.43) | NR1H4NPC1RAB9ATDP1L3MBTL1 | |
| SCHEMBL27929301 | 0.87 | SMN1; SMN2 (0.40) | NR1H4NPC1RAB9ATDP1L3MBTL1 | |
| SCHEMBL28806569 | 0.79 | NR1H4 (0.36) | NR1H4NPC1RAB9ATDP1L3MBTL1 | |
| SCHEMBL27929313 | 0.76 | HRH4 (0.43) | RAB9ACNR1CNR2SMN1; SMN2MEN1 | |
| SCHEMBL27929330 | 0.72 | SMN1; SMN2 (0.48) | RAB9AL3MBTL1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL514454 | 0.71 | SLC16A3 (0.45) | NPC1RAB9ATDP1L3MBTL1SMN1; SMN2 | |
| SCHEMBL513268 | 0.71 | SLC16A3 (0.42) | NR1H4NPC1RAB9ATDP1L3MBTL1 | |
| SCHEMBL513313 | 0.70 | SMN1; SMN2 (0.42) | NPC1RAB9ATDP1L3MBTL1SMN1; SMN2 | |
| SCHEMBL24038948 | 0.70 | MAPT (0.56) | TDP1L3MBTL1SMN1; SMN2LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103467481-A | Dihydropyridine compounds, compositions thereof, preparation method and applications | SHANGHAI HUILUN LIFE SCIENCE & TECHNOLOGY CO LTD | 2013-12-25 | — | — | CN | disclosed |