Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC16A3 | O15427 | 2/20 | 0.42 |
| ▸ | SLC16A1 | P53985 | 2/20 | 0.42 |
| ▸ | MCTS1 | Q9ULC4 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL514454 | 0.88 | SLC16A3 (0.45) | SLC16A3SLC16A1MCTS1NPC1RAB9A | |
| SCHEMBL22613680 | 0.78 | SLC16A3 (0.51) | SLC16A3SLC16A1MCTS1SMN1; SMN2LMNA | |
| SCHEMBL20600034 | 0.75 | MAPK14 (0.45) | SLC16A3SLC16A1MCTS1SMN1; SMN2L3MBTL1 | |
| SCHEMBL513313 | 0.75 | SMN1; SMN2 (0.42) | NPC1RAB9ASMN1; SMN2PKMTDP1 | |
| SCHEMBL513238 | 0.75 | SMN1; SMN2 (0.41) | SLC16A3SLC16A1MCTS1NPC1RAB9A | |
| SCHEMBL513700 | 0.74 | ALDH1A1 (0.36) | SLC16A3SLC16A1MCTS1NPC1RAB9A | |
| SCHEMBL20600256 | 0.74 | NPC1 (0.47) | SLC16A3SLC16A1MCTS1NPC1RAB9A | |
| SCHEMBL24038948 | 0.72 | MAPT (0.56) | SMN1; SMN2TDP1L3MBTL1LMNAMEN1 | |
| SCHEMBL27946641 | 0.71 | NR1H4 (0.42) | NPC1RAB9ASMN1; SMN2PKMTDP1 | |
| SCHEMBL10475753 | 0.70 | NPC1 (0.45) | NPC1RAB9ASMN1; SMN2PKMTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120028931-A1 | HETEROCYCLIC M-GLU5 ANTAGONISTS | RECORDATI IRELAND LIMITED (IE) | 2012-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120028931-A1 | HETEROCYCLIC M-GLU5 ANTAGONISTS | OPRM1, GRM5, OPRD1 | SLC16A3 685/4885SLC16A1 753/4885MCTS1 1473/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.