Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.50 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.50 |
| ▸ | PIM1 | P11309 | 10/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.46 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.43 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.43 |
| ▸ | CLK2 | P49760 | 3/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.43 |
| ▸ | CLK3 | P49761 | 2/20 | 0.43 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.42 |
| ▸ | AXL | P30530 | 1/20 | 0.41 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.41 |
| ▸ | WNT1 | P04628 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2926259 | 0.82 | PIM1 (0.51) | IDO1LRRK2PIM1PIM2PIM3 | |
| SCHEMBL1513056 | 0.80 | ALDH1A1 (0.55) | IDO1LRRK2PIM1PIM2PIM3 | |
| SCHEMBL30931548 | 0.80 | ALDH1A1 (0.55) | IDO1LRRK2PIM1PIM2PIM3 | |
| SCHEMBL17922026 | 0.78 | LRRK2 (0.41) | IDO1LRRK2PIM1CYP2A6PIM2 | |
| SCHEMBL29930912 | 0.78 | MAPK1 (0.42) | IDO1LRRK2PIM1DYRK1A | |
| SCHEMBL25029271 | 0.76 | ALDH1A1 (0.54) | PIM1MAP2K4GRM4 | |
| SCHEMBL9877148 | 0.76 | PDPK1 (0.49) | IDO1LRRK2MAP2K4 | |
| SCHEMBL10452107 | 0.74 | LRRK2 (0.62) | IDO1LRRK2MAP2K4GRM4 | |
| SCHEMBL1639739 | 0.74 | LRRK2 (0.67) | IDO1LRRK2PIM1CYP2A6PIM2 | |
| SCHEMBL18449016 | 0.74 | CLK2 (0.61) | CLK2DYRK1ACLK3WNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105503862-B | Inhibitors of influenza viruses replication | 沃泰克斯药物股份有限公司 | 2018-02-02 | — | — | CN | disclosed |
| CN-103492381-A | Inhibitors of influenza virus replication | VERTEX PHARMA | 2014-01-01 | — | — | CN | disclosed |