Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.56 |
| ▸ | ACHE | P22303 | 1/20 | 0.56 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.49 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.49 |
| ▸ | HTR3B | O95264 | 2/20 | 0.49 |
| ▸ | HTR3A | P46098 | 2/20 | 0.49 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.49 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.49 |
| ▸ | THPO | P40225 | 1/20 | 0.49 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4574459 | 0.82 | HRH3 (0.54) | HRH3HTTKDM4EALDH1A1CYP1A2 | |
| SCHEMBL30838169 | 0.78 | HRH3 (0.46) | HRH3HTTKDM4EALDH1A1CYP1A2 | |
| SCHEMBL6766547 | 0.77 | HTR2C (0.57) | HRH3HTTKDM4EALDH1A1CYP1A2 | |
| SCHEMBL14890430 | 0.74 | ASIC3 (0.49) | BCHEACHELMNAHTTSMN1; SMN2 | |
| SCHEMBL8322135 | 0.74 | PDE10A (0.49) | HRH3HTTKDM4EALDH1A1CYP1A2 | |
| SCHEMBL8322172 | 0.74 | PDE10A (0.64) | HRH3HTTKDM4EALDH1A1CYP1A2 | |
| SCHEMBL8322138 | 0.74 | PDE10A (0.64) | HRH3HTTKDM4EALDH1A1CYP1A2 | |
| SCHEMBL29058206 | 0.74 | HRH3 (0.48) | HRH3HTTKDM4EALDH1A1CYP1A2 | |
| SCHEMBL5664122 | 0.73 | HRH3 (0.71) | HRH3LMNAHTTSMN1; SMN2KDM4E | |
| SCHEMBL29604668 | 0.73 | HRH3 (0.71) | HRH3LMNAHTTSMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103459382-A | Heterocyclic compounds for the inhibition of pask | BIOENERGENIX LLC | 2013-12-18 | — | — | CN | disclosed |