Triphosphate

Triphosphate

SCHEMBL27947677

Cc1cn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)nc1N.O=P(O)(O)OP(=O)(O)OP(=O)(O)O

nearest known ligand 0.65

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ P2RY2 P41231 7/20 0.53
▸ LMNA P02545 2/20 0.51
▸ MTOR P42345 2/20 0.51
▸ THRB P10828 1/20 0.51
▸ MDM2 Q00987 1/20 0.51
▸ NCOA1 Q15788 1/20 0.51
▸ NCOA3 Q9Y6Q9 1/20 0.51
▸ GMNN O75496 1/20 0.51
▸ ALDH1A1 P00352 1/20 0.51
▸ TP53 P04637 1/20 0.51
▸ NFKB1 P19838 1/20 0.51
▸ DNMT1 P26358 1/20 0.51
▸ THPO P40225 1/20 0.51
▸ HTT P42858 1/20 0.51
▸ RAB9A P51151 1/20 0.51
▸ BLM P54132 1/20 0.51
▸ HBB P68871 1/20 0.51
▸ PMP22 Q01453 1/20 0.51
▸ P2RY6 Q15077 4/20 0.48
▸ P2RY4 P51582 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Triphosphate SCHEMBL28043838 1.00 P2RY2 (0.53) P2RY2LMNAMTORTHRBMDM2
Pyrophosphoric Acid SCHEMBL14661255 0.96 LMNA (0.53) P2RY2LMNAMTORTHRBMDM2
Phosphoric Acid SCHEMBL27959721 0.92 LMNA (0.57) LMNAMTORTHRBMDM2NCOA1
Phosphoric Acid SCHEMBL14661092 0.92 LMNA (0.57) LMNAMTORTHRBMDM2NCOA1
Phosphoric Acid SCHEMBL667968 0.92 LMNA (0.57) LMNAMTORTHRBMDM2NCOA1
SCHEMBL17803620 0.89 LMNA (0.55) LMNAMTORTHRBMDM2NCOA1
SCHEMBL31348019 0.89 RNASEL (0.49) P2RY2P2RY6P2RY4ENPP1P2RY1
SCHEMBL41572 0.89 LMNA (0.62) LMNAMTORTHRBMDM2NCOA1
SCHEMBL18512948 0.89 LMNA (0.62) LMNAMTORTHRBMDM2NCOA1
SCHEMBL2579580 0.89 LMNA (0.62) LMNAMTORTHRBMDM2NCOA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105142676-A CFTR MRNA compositions and related methods and uses SHIRE HUMAN GENETIC THERAPIES 2015-12-09 — — CN claimed
CN-105765387-B Method for determining the posttranslational modification in peptide, polypeptide or protein 牛津大学创新有限公司 2019-10-18 — — CN disclosed
CN-110168104-A METHODS AND SYSTEMS FOR CHARACTERIZING ANALYTES USING NANOPORES 牛津纳米孔技术公司 2019-08-23 — — CN disclosed
CN-110121562-A Method of producing a composite material 牛津纳米孔技术公司 2019-08-13 — — CN disclosed
CN-110088299-A Nanopore-directed nucleic acid detection methods 牛津纳米孔技术公司 2019-08-02 — — CN disclosed
CN-109983119-A GLYCOENGINEERING OF E-SELECTIN LIGANDS 罗伯特·萨克斯坦 2019-07-05 — — CN disclosed
CN-109803977-A NUCLEIC ACID PRODUCTS AND METHODS OF ADMINISTRATION THEREOF 菲克特生物科学股份有限公司 2019-05-24 — — CN disclosed
CN-109526226-A Compositions and methods relating to therapeutic cell systems expressing exogenous RNA 鲁比厄斯治疗法股份有限公司 2019-03-26 — — CN disclosed
CN-109477102-A Nucleic acid product and its method of administration 菲克特生物科学股份有限公司 2019-03-15 — — CN disclosed
CN-109415723-A IMPROVED PROMOTERS AND COMPOSITIONS 牛津大学创新有限公司 2019-03-01 — — CN disclosed
CN-106574298-A Methods and compositions for sample analysis 10X基因组学有限公司 2017-04-19 — — CN disclosed
CN-104321441-B The survey quantitative analysis of polymer 牛津楠路珀尔科技有限公司 2016-10-19 — — CN disclosed
CN-105765387-A Method 伊希斯创新有限公司 2016-07-13 — — CN disclosed
CN-105142396-A Hornless livestock RECOMBINETICS INC 2015-12-09 — — CN disclosed
CN-104519915-A Pulmonary delivery of mRNA to non-lung target cells SHIRE HUMAN GENETIC THERAPIES 2015-04-15 — — CN disclosed
CN-104350067-A Mutant lysenin pore OXFORD NANOPORE TECH LTD 2015-02-11 — — CN disclosed
CN-104321441-A Analysis of measurements of a polymer OXFORD NANOPORE TECH LTD 2015-01-28 — — CN disclosed
CN-104220874-A Aptamer method OXFORD NANOPORE TECH LTD 2014-12-17 — — CN disclosed
CN-103827320-A Hairpin loop method for sequencing double-stranded polynucleotides using transmembrane pores OXFORD NANOPORE TECH LTD 2014-05-28 — — CN disclosed
CN-103502436-A Method for transfecting cells with nucleic acids MASSACHUSETTS INST TECHNOLOGY 2014-01-08 — — CN disclosed
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