SCHEMBL279483

SCHEMBL279483

CC(=O)/C=C/c1ccc([N+](=O)[O-])cc1

nearest known ligand 0.69

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.69
KMT2A Q03164 3/20 0.69
MAOB P27338 7/20 0.62
MAOA P21397 5/20 0.62
BCHE P06276 1/20 0.61
APP P05067 1/20 0.58
CYP1B1 Q16678 1/20 0.57
FBP1 P09467 1/20 0.56
POLB P06746 2/20 0.55
HSPD1 P10809 1/20 0.55
HSPE1 P61604 1/20 0.55
MAPT P10636 1/20 0.55
GLA P06280 1/20 0.55
TDP1 Q9NUW8 1/20 0.55
APEX1 P27695 1/20 0.55
PTGS1 P23219 1/20 0.54
PTGS2 P35354 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15238912 1.00 MEN1 (0.69) MEN1KMT2AMAOBMAOABCHE
SCHEMBL811912 1.00 MEN1 (0.69) MEN1KMT2AMAOBMAOABCHE
SCHEMBL9778220 0.85 MEN1 (0.69) MEN1KMT2AMAOBMAOABCHE
SCHEMBL11702342 0.85 MEN1 (0.69) MEN1KMT2AMAOBMAOABCHE
SCHEMBL13710801 0.84 MEN1 (0.62) MEN1KMT2AMAOBMAOABCHE
SCHEMBL5020752 0.83 HDAC1 (0.77) MEN1KMT2AMAPTTDP1
SCHEMBL277169 0.83 MEN1 (0.71) MEN1KMT2AMAOBMAOABCHE
SCHEMBL27971259 0.83 MAOB (0.63) MEN1KMT2AMAOBMAOABCHE
SCHEMBL27888906 0.83 MAOB (0.63) MEN1KMT2AMAOBMAOABCHE
SCHEMBL42325 0.83 MEN1 (0.71) MEN1KMT2AMAOBMAOABCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 157 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4431567-A2 PROCESS FOR STABILIZING A COMPOSITION OF POLYARYL-ETHER-KETONE (PAEK) ARKEMA FRANCE (FR) 2024-09-18 EP claimed
CN-117624864-A Chemical-resistant polycarbonate composition and preparation method thereof 广东圆融新材料有限公司 2024-03-01 CN claimed
EP-4292586-A1 GUANFACINE HYDROCHLORIDE CONTAINING PHARMACEUTICAL PREPARATION Sawai Pharmaceutical Co., Ltd. (JP) 2023-12-20 EP claimed
EP-4292587-A1 GUANFACINE HYDROCHLORIDE CONTAINING PHARMACEUTICAL PREPARATION Sawai Pharmaceutical Co., Ltd. (JP) 2023-12-20 EP claimed
WO-2023197401-A1 BIOLOGICAL GEL FORMULATION, METHOD FOR PREPARING SAME, AND USE THEREOF 臻赫医药(杭州)有限公司 2023-10-19 WO claimed
CN-116440072-A Single-dose atropine ophthalmic composition for delaying myopia progression and BFS sterile production method thereof 北京中科利华医药研究院有限公司 2023-07-18 CN claimed
CN-115708800-A Eye drop composition of sitagliptin and tea polyphenol 上海博悦生物科技有限公司 2023-02-24 CN claimed
CN-115252916-A Medical hollow magnesium or magnesium alloy implant and preparation method thereof 大博医疗科技股份有限公司 2022-11-01 CN claimed
CN-115154655-A Medical metal implant and processing method thereof 大博医疗科技股份有限公司 2022-10-11 CN claimed
WO-2022135343-A1 VILAZODONE PHARMACEUTICAL COMPOSITION, PREPARATION METHOD THEREFOR AND USE THEREOF 上海博志研新药物技术有限公司 2022-06-30 WO claimed
WO-2022121961-A1 FULVESTRANT PHARMACEUTICAL COMPOSITION, PREPARATION THEREFOR, AND APPLICATION THEREOF 上海博志研新药物技术有限公司 2022-06-16 WO claimed
CN-109652463-A A method of using Perakine reductase synthesis of chiral alcohol 浙江大学 2019-04-19 CN claimed
EP-4659755-A1 THERAPEUTIC DRUG FOR RETINAL PIGMENT EPITHELIUM TEARS RACTHERA Co., Ltd. (JP) 2025-12-10 EP disclosed
EP-4654902-A1 MEDICAL DEVICE FOR REGENERATING BONE AND A METHOD OF MANUFACTURE THEREOF PBC Innovations Limited (IE) 2025-12-03 EP disclosed
US-12465593-B2 Pharmaceutical composition ASTRAZENECA AB (SE) 2025-11-11 US disclosed
EP-4595952-A1 OPHTHALMIC COMPOSITION COMPRISING BRIMONIDINE Taejoon Pharmaceutical Co., Ltd. (KR) 2025-08-06 EP disclosed
EP-0034349-B1 NOVEL PYRIDINECARBOXAMIDE DERIVATIVES, A PROCESS FOR THE PREPARATION THEREOF, THE USE OF SAID DERIVATIVES AND A PHARMACEUTICAL COMPOSITION CONTAINING SAME Tanabe Seiyaku Co., Ltd. (JP) 1983-12-14 EP disclosed
US-4332809-A ANTIALLERGENS TANABE SEIYAKU CO., LTD. (JP) 1982-06-01 US disclosed
EP-0034349-A2 Novel pyridinecarboxamide derivatives, a process for the preparation thereof, the use of said derivatives and a pharmaceutical composition containing same Tanabe Seiyaku Co., Ltd. (JP) 1981-08-26 EP disclosed
US-3989708-A HYPOTENSIVE, CORONARY VESSEL DILATORS BAYER AKTIENGESELLSCHAFT (DT) 1976-11-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12465593-B2 Pharmaceutical composition CYP3A7, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, UGT2B7 MEN1 2963/4885KMT2A 1214/4885MAOB 2360/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.