Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 2/20 | 0.39 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27948360 | 0.82 | GSK3B (0.44) | HTR2CSMN1; SMN2GSK3BSLC6A3 | |
| SCHEMBL25282803 | 0.80 | HTR2C (0.42) | HTR2CGSK3BALDH1A1PDE10ASLC6A2 | |
| SCHEMBL25240045 | 0.80 | HTR2C (0.42) | HTR2CGSK3BALDH1A1PDE10ASLC6A2 | |
| SCHEMBL10388908 | 0.79 | KDM4E (0.44) | GSK3BALDH1A1PDE10A | |
| SCHEMBL27906101 | 0.77 | PRCP (0.39) | GSK3BALDH1A1PDE10AMAPT | |
| SCHEMBL25353405 | 0.77 | BRD4 (0.38) | HTR2CTSHR | |
| SCHEMBL23222196 | 0.77 | MAOB (0.39) | HTR2CMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL25358394 | 0.77 | BRD4 (0.38) | HTR2CTSHR | |
| SCHEMBL25354550 | 0.74 | MAOB (0.37) | HTR2CALDH1A1 | |
| SCHEMBL18997553 | 0.73 | BRD4 (0.39) | HTR2CMEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017112777-A1 | COMPOUNDS FOR THE TREATMENT OF CANCER AND INFLAMMATORY DISEASE | SHY Therapeutics LLC (US) | 2017-06-29 | — | — | WO | disclosed |