Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | TNF | P01375 | 1/20 | 0.48 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.48 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13479895 | 0.85 | TDP1 (0.53) | ALDH1A1TDP1MAPTL3MBTL1LMNA | |
| SCHEMBL10913990 | 0.76 | RAB9A (0.50) | ALDH1A1NPC1RAB9ARECQLLMNA | |
| SCHEMBL31715823 | 0.76 | TDP1 (0.69) | ALDH1A1NPC1RAB9ATDP1MAPT | |
| SCHEMBL10488502 | 0.75 | RAB9A (0.69) | ALDH1A1NPC1RAB9ARECQLTDP1 | |
| SCHEMBL12930116 | 0.74 | MAPK1 (0.65) | ALDH1A1NPC1RAB9ARECQLTDP1 | |
| SCHEMBL12930117 | 0.74 | MAPK1 (0.65) | ALDH1A1NPC1RAB9ARECQLTDP1 | |
| SCHEMBL9878491 | 0.73 | TDP1 (0.69) | ALDH1A1NPC1RAB9ARECQLTDP1 | |
| SCHEMBL446400 | 0.73 | TDP1 (0.69) | ALDH1A1NPC1RAB9ARECQLTDP1 | |
| SCHEMBL18320469 | 0.73 | KMT2A (0.69) | ALDH1A1NPC1RAB9ATDP1MAPT | |
| SCHEMBL27933271 | 0.72 | PLCG1 (0.51) | ALDH1A1NPC1RAB9ATDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103509135-A | Olefin polymerization catalyst component, preparation method and application thereof | CHINA PETROLEUM & CHEMICAL | 2014-01-15 | — | — | CN | disclosed |