SCHEMBL27933271

SCHEMBL27933271

O=C(OCS(=O)(=O)c1ccccc1Br)c1ccccc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLCG1 P19174 1/20 0.51
TDP1 Q9NUW8 2/20 0.46
NPC1 O15118 1/20 0.45
HPGD P15428 1/20 0.45
RAB9A P51151 1/20 0.45
MAPK1 P28482 1/20 0.45
HIF1A Q16665 1/20 0.45
SLC6A2 P23975 1/20 0.45
SLC6A3 Q01959 1/20 0.45
KMT2A Q03164 1/20 0.45
ALDH1A1 P00352 4/20 0.44
LMNA P02545 2/20 0.44
POLB P06746 2/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
CA4 P22748 1/20 0.42
CA6 P23280 1/20 0.42
TSHR P16473 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP2C9 P11712 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13479895 0.78 TDP1 (0.53) TDP1HPGDMAPK1HIF1ASLC6A2
SCHEMBL27948827 0.76 ALDH1A1 (0.49) PLCG1TDP1NPC1HPGDRAB9A
SCHEMBL28911450 0.76 PLCG1 (0.56) PLCG1TDP1NPC1HPGDRAB9A
SCHEMBL6203315 0.75 PLCG1 (0.44) PLCG1TDP1NPC1HPGDRAB9A
SCHEMBL27544607 0.74 TDP1 (0.57) TDP1NPC1HPGDRAB9AMAPK1
SCHEMBL27933035 0.73 HSD11B1 (0.63) PLCG1TDP1KMT2AALDH1A1LMNA
SCHEMBL27669121 0.73 TDP1 (0.55) TDP1NPC1HPGDRAB9AMAPK1
SCHEMBL6203312 0.73 PLCG1 (0.45) PLCG1TDP1NPC1HPGDRAB9A
SCHEMBL1926517 0.72 POLB (0.46) PLCG1KMT2AALDH1A1LMNAPOLB
SCHEMBL27948822 0.72 ALDH1A1 (0.56) TDP1NPC1RAB9AMAPK1HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103509135-A Olefin polymerization catalyst component, preparation method and application thereof CHINA PETROLEUM & CHEMICAL 2014-01-15 CN disclosed