SCHEMBL27948831

SCHEMBL27948831

CCCCS(=O)(=O)c1ccccc1OC(=O)c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.46
MAPT P10636 3/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
SLC6A3 Q01959 1/20 0.46
HSD17B10 Q99714 2/20 0.44
MEN1 O00255 2/20 0.44
NPSR1 Q6W5P4 2/20 0.44
JAK2 O60674 1/20 0.44
USP2 O75604 1/20 0.44
ESR1 P03372 1/20 0.44
GAA P10253 1/20 0.44
ALOX15 P16050 1/20 0.44
ESR2 Q92731 1/20 0.44
LMNA P02545 2/20 0.43
PARP1 P09874 1/20 0.40
TSHR P16473 1/20 0.40
KDM4E B2RXH2 1/20 0.40
RECQL P46063 1/20 0.40
L3MBTL1 Q9Y468 2/20 0.39
TDP1 Q9NUW8 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28023030 0.92 KMT2A (0.49) KMT2AMAPTSMN1; SMN2SLC6A3HSD17B10
SCHEMBL27933199 0.87 KMT2A (0.53) KMT2AMAPTSMN1; SMN2SLC6A3HSD17B10
SCHEMBL27933064 0.79 NPSR1 (0.44) KMT2AMAPTSMN1; SMN2SLC6A3HSD17B10
SCHEMBL20314686 0.77 HTR6 (0.50)
SCHEMBL6755928 0.76 EPHX2 (0.46) KMT2AMAPTSLC6A3MEN1LMNA
SCHEMBL38811 0.76 KMT2A (0.58) KMT2AMAPTSMN1; SMN2SLC6A3HSD17B10
SCHEMBL5815925 0.76 KMT2A (0.58) KMT2AMAPTSMN1; SMN2SLC6A3HSD17B10
SCHEMBL31098906 0.76 KMT2A (0.58) KMT2AMAPTSMN1; SMN2SLC6A3HSD17B10
SCHEMBL9726257 0.75 TSHR (0.54) KMT2AMAPTSMN1; SMN2MEN1ESR1
SCHEMBL28023653 0.75 KAT6A (0.46) KMT2AMAPTSMN1; SMN2MEN1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106496367-A Catalytic component and its preparation and application for olefinic polymerization 中国石油化工股份有限公司 2017-03-15 CN disclosed
CN-103509135-B Olefin polymerization catalyst component, preparation method and application thereof CHINA PETROLEUM & CHEMICAL 2015-07-22 CN disclosed
CN-103509135-A Olefin polymerization catalyst component, preparation method and application thereof CHINA PETROLEUM & CHEMICAL 2014-01-15 CN disclosed