Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | ESR1 | P03372 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.54 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.54 |
| ▸ | STS | P08842 | 7/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9726266 | 0.95 | ALDH1A1 (0.54) | TSHRLMNACYP1A2CYP2C19MAPK1 | |
| SCHEMBL9726277 | 0.92 | LMNA (0.56) | TSHRLMNACYP1A2CYP2C19MAPK1 | |
| SCHEMBL9726258 | 0.88 | POLB (0.49) | TSHRLMNACYP1A2CYP2C19MAPK1 | |
| SCHEMBL9732670 | 0.88 | TSHR (0.51) | TSHRLMNACYP1A2CYP2C19MAPK1 | |
| SCHEMBL9726262 | 0.87 | SMN1; SMN2 (0.50) | LMNACYP1A2CYP2C19SMN1; SMN2ESR1 | |
| SCHEMBL9726263 | 0.83 | MAPT (0.52) | TSHRLMNACYP1A2CYP2C19MAPK1 | |
| SCHEMBL27922199 | 0.81 | TSHR (0.59) | TSHRLMNACYP1A2CYP2C19MAPK1 | |
| SCHEMBL9726303 | 0.80 | LMNA (0.54) | TSHRLMNACYP1A2CYP2C19MAPK1 | |
| SCHEMBL9726298 | 0.79 | SLC6A3 (0.54) | TSHRSMN1; SMN2STSMAPTTDP1 | |
| SCHEMBL9352810 | 0.79 | ELANE (0.52) | TSHRLMNAMAPK1STSCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5078907-A | UNSYMMETRICAL DICARBOXYLIC ESTERS AS BLEACH PRECURSORS | LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) | 1992-01-07 | — | — | US | disclosed |