Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 13/20 | 0.55 |
| ▸ | NPC1 | O15118 | 12/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1312698 | 0.81 | RAB9A (0.55) | RAB9ANPC1MEN1KMT2ANOTUM | |
| SCHEMBL29287229 | 0.81 | RAB9A (0.55) | RAB9ANPC1MEN1KMT2ANOTUM | |
| SCHEMBL20982156 | 0.73 | RAB9A (0.46) | RAB9ANPC1MEN1KMT2ANOTUM | |
| 3,5-Diphenylisoxazole SCHEMBL1421260 | 0.71 | NPC1 (1.00) | RAB9ANPC1MEN1KMT2ANOTUM | |
| SCHEMBL19379939 | 0.71 | RAB9A (0.63) | RAB9ANPC1MEN1KMT2ANOTUM | |
| SCHEMBL27847622 | 0.71 | RAB9A (0.62) | RAB9ANPC1MEN1KMT2ANOTUM | |
| SCHEMBL8524434 | 0.69 | RAB9A (0.61) | RAB9ANPC1MEN1KMT2ANOTUM | |
| SCHEMBL224856 | 0.69 | RAB9A (0.61) | RAB9ANPC1MEN1KMT2ANOTUM | |
| SCHEMBL354043 | 0.69 | RAB9A (0.61) | RAB9ANPC1MEN1KMT2ANOTUM | |
| SCHEMBL929198 | 0.69 | RAB9A (0.61) | RAB9ANPC1MEN1KMT2ANOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103508950-B | Containing 4-hydroxyl-2-quinolinones compound and the Synthesis and applications thereof of imine structure | NANKAI UNIVERSITY (CN) | 2016-04-20 | — | — | CN | disclosed |
| CN-103508950-A | 4-hydroxy-2-quinolinone compounds containing imine structure, and preparation and application thereof | UNIV NANKAI | 2014-01-15 | — | — | CN | disclosed |