Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 12/20 | 0.61 |
| ▸ | NPC1 | O15118 | 11/20 | 0.61 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.53 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.50 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.50 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19379939 | 0.76 | RAB9A (0.63) | RAB9ANPC1MEN1KMT2ANOTUM | |
| 3,5-Diphenylisoxazole SCHEMBL1421260 | 0.76 | NPC1 (1.00) | RAB9ANPC1MEN1KMT2ANOTUM | |
| SCHEMBL929198 | 0.74 | RAB9A (0.61) | RAB9ANPC1MEN1KMT2ANOTUM | |
| SCHEMBL4853385 | 0.74 | RAB9A (0.61) | RAB9ANPC1MEN1KMT2ANOTUM | |
| SCHEMBL8258186 | 0.74 | NPC1 (0.96) | RAB9ANPC1MEN1KMT2ANOTUM | |
| SCHEMBL224856 | 0.74 | RAB9A (0.61) | RAB9ANPC1MEN1KMT2ANOTUM | |
| SCHEMBL12959175 | 0.74 | RAB9A (0.61) | RAB9ANPC1MEN1KMT2ANOTUM | |
| SCHEMBL3751941 | 0.74 | RAB9A (0.61) | RAB9ANPC1MEN1KMT2ANOTUM | |
| SCHEMBL16519877 | 0.74 | RAB9A (0.61) | RAB9ANPC1MEN1KMT2ANOTUM | |
| SCHEMBL354043 | 0.74 | RAB9A (0.61) | RAB9ANPC1MEN1KMT2ANOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5952359-A | NEMATICIDES, INSECTICIDES AND MITICIDES; 1,1-DIFLUORO-3-(THIAZOLYL OR ISOTHIAZOYL-THIO (OR SULFINYL OR SULFONYL)-PROP-1-ENE DERIVATIVES | ZENECA LIMITED (GB) | 1999-09-14 | — | — | US | disclosed |