Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRR | Q9GZT4 | 3/20 | 0.51 |
| ▸ | PPARG | P37231 | 12/20 | 0.44 |
| ▸ | PPARA | Q07869 | 11/20 | 0.44 |
| ▸ | ACE | P12821 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | ALPI | P09923 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | XIAP | P98170 | 1/20 | 0.43 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.43 |
| ▸ | PSAT1 | Q9Y617 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10874175 | 1.00 | SRR (0.51) | SRRPPARGPPARAACEEPHX1 | |
| SCHEMBL28982634 | 0.83 | SRR (0.58) | SRRPPARGPPARAACEEPHX1 | |
| SCHEMBL7276245 | 0.83 | PPARG (0.45) | PPARGPPARAEPHX1 | |
| SCHEMBL7276239 | 0.83 | PPARG (0.45) | PPARGPPARAEPHX1 | |
| SCHEMBL15757776 | 0.81 | LMNA (0.48) | PPARGPPARAACEALDH1A1SMN1; SMN2 | |
| SCHEMBL7454107 | 0.81 | SRR (0.51) | SRRPPARGPPARAACEEPHX1 | |
| SCHEMBL7454461 | 0.81 | SRR (0.51) | SRRPPARGPPARAACEEPHX1 | |
| SCHEMBL7454095 | 0.81 | SRR (0.51) | SRRPPARGPPARAACEEPHX1 | |
| SCHEMBL395105 | 0.80 | SRR (0.47) | SRRPPARGPPARAACEEPHX1 | |
| SCHEMBL28336186 | 0.80 | SRR (0.54) | SRRPPARGPPARAACEEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113430240-B | Method for synthesizing atazanavir intermediate chlorohydrin by continuous flow biocatalysis | 华东理工大学 | 2023-07-04 | — | — | CN | claimed |
| CN-113249348-B | Carbonyl reductase, gene thereof, recombinant expression transformant containing the gene and use thereof | 华东理工大学 | 2023-06-23 | — | — | CN | claimed |
| CN-113430240-A | Method for synthesizing atazanavir intermediate chlorohydrin by continuous flow biocatalysis | 华东理工大学 | 2021-09-24 | — | — | CN | claimed |
| CN-113249348-A | Carbonyl reductase, gene thereof, recombinant expression transformant containing gene and application of recombinant expression transformant | 华东理工大学 | 2021-08-13 | — | — | CN | claimed |
| CN-107354179-B | Method for preparing chiral compound containing hydroxyl | 上海医药工业研究院 | 2021-02-19 | — | — | CN | claimed |
| CN-113430240-B | Method for synthesizing atazanavir intermediate chlorohydrin by continuous flow biocatalysis | 华东理工大学 | 2023-07-04 | — | — | CN | disclosed |
| CN-113430240-B | Method for synthesizing atazanavir intermediate chlorohydrin by continuous flow biocatalysis | 华东理工大学 | 2023-07-04 | — | — | CN | disclosed |
| CN-113249348-B | Carbonyl reductase, gene thereof, recombinant expression transformant containing the gene and use thereof | 华东理工大学 | 2023-06-23 | — | — | CN | disclosed |
| CN-113249348-B | Carbonyl reductase, gene thereof, recombinant expression transformant containing the gene and use thereof | 华东理工大学 | 2023-06-23 | — | — | CN | disclosed |
| CN-113430240-A | Method for synthesizing atazanavir intermediate chlorohydrin by continuous flow biocatalysis | 华东理工大学 | 2021-09-24 | — | — | CN | disclosed |
| CN-113430240-A | Method for synthesizing atazanavir intermediate chlorohydrin by continuous flow biocatalysis | 华东理工大学 | 2021-09-24 | — | — | CN | disclosed |
| CN-113249348-A | Carbonyl reductase, gene thereof, recombinant expression transformant containing gene and application of recombinant expression transformant | 华东理工大学 | 2021-08-13 | — | — | CN | disclosed |
| CN-113249348-A | Carbonyl reductase, gene thereof, recombinant expression transformant containing gene and application of recombinant expression transformant | 华东理工大学 | 2021-08-13 | — | — | CN | disclosed |
| CN-107354179-B | Method for preparing chiral compound containing hydroxyl | 上海医药工业研究院 | 2021-02-19 | — | — | CN | disclosed |
| CN-103468757-A | Biological preparation method of intermediate of atazanavir | ENZYMEWORKS INC | 2013-12-25 | — | — | CN | disclosed |