Diphenylmethane

Diphenylmethane

SCHEMBL27949482

NOC(N)=O.c1ccc(Cc2ccccc2)cc1

nearest known ligand 0.61

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLA2G10 O15496 1/20 0.61
PLA2G2A P14555 1/20 0.61
CALM1 P0DP23 1/20 0.55
LMNA P02545 2/20 0.50
SLC22A2 O15244 1/20 0.48
SRR Q9GZT4 2/20 0.47
PRSS1 P07477 1/20 0.46
PRSS2 P07478 1/20 0.46
PRSS3 P35030 1/20 0.46
PPARG P37231 3/20 0.44
PPARA Q07869 3/20 0.44
CES2 O00748 1/20 0.44
CES1 P23141 1/20 0.44
AKR1B1 P15121 1/20 0.44
IDO1 P14902 1/20 0.44
SRD5A2 P31213 1/20 0.44
HNF4A P41235 1/20 0.44
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
HDAC8 Q9BY41 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Diphenylmethane SCHEMBL18604552 0.85 PLA2G10 (0.71) PLA2G10PLA2G2ACALM1LMNASLC22A2
Diphenylmethane SCHEMBL8743340 0.85 PLA2G10 (0.71) PLA2G10PLA2G2ACALM1LMNASLC22A2
Diphenylmethane SCHEMBL28144267 0.85 PLA2G10 (0.71) PLA2G10PLA2G2ACALM1LMNASLC22A2
Diphenylmethane SCHEMBL10451543 0.85 PLA2G10 (0.71) PLA2G10PLA2G2ACALM1LMNASLC22A2
Benzyl Alcohol SCHEMBL2198856 0.84 TSHR (0.61) PLA2G10PLA2G2ALMNASRRPPARG
Diphenylmethane SCHEMBL11255043 0.84 PLA2G10 (0.59) PLA2G10PLA2G2ACALM1LMNASLC22A2
Diphenylmethane SCHEMBL4912413 0.81 PLA2G10 (0.65) PLA2G10PLA2G2ACALM1LMNASLC22A2
Diphenylmethane SCHEMBL5607610 0.80 CALM1 (0.75) PLA2G10PLA2G2ACALM1LMNACES2
Diphenylmethane SCHEMBL8658678 0.80 CALM1 (0.75) PLA2G10PLA2G2ACALM1LMNACES2
Diphenylmethane SCHEMBL29127396 0.80 CALM1 (0.75) PLA2G10PLA2G2ACALM1LMNACES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103534231-A Process for preparing polymethylene polyphenyl polycarbamates INST PROCESS ENG CAS 2014-01-22 CN disclosed