Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 5/20 | 0.35 |
| ▸ | PPARA | Q07869 | 4/20 | 0.35 |
| ▸ | RXRA | P19793 | 4/20 | 0.35 |
| ▸ | RXRB | P28702 | 2/20 | 0.35 |
| ▸ | RARA | P10276 | 2/20 | 0.34 |
| ▸ | RARB | P10826 | 2/20 | 0.34 |
| ▸ | RARG | P13631 | 2/20 | 0.34 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.33 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.33 |
| ▸ | CCR9 | P51686 | 1/20 | 0.33 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.32 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.32 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | PPARD | Q03181 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27936028 | 0.91 | RXRA (0.36) | PPARGPPARARXRARXRBRARA | |
| SCHEMBL27936024 | 0.90 | PPARG (0.39) | PPARGPPARASRD5A2PPARD | |
| Piperazine SCHEMBL27950239 | 0.86 | PPARG (0.36) | PPARGPPARAPPARD | |
| SCHEMBL28810371 | 0.85 | MEN1 (0.36) | PPARGSRD5A2 | |
| SCHEMBL27884360 | 0.83 | PPARG (0.38) | PPARGPPARASRD5A2PPARD | |
| SCHEMBL27950252 | 0.83 | PPARG (0.38) | PPARGPPARANR1H4PPARD | |
| SCHEMBL12096889 | 0.82 | PPARG (0.50) | PPARGPPARARXRARXRBRARA | |
| SCHEMBL27936027 | 0.81 | PPARG (0.39) | PPARGPPARASRD5A2NR1H4PPARD | |
| SCHEMBL27936038 | 0.81 | PPARG (0.38) | PPARGPPARAPPARD | |
| SCHEMBL27936050 | 0.81 | PPARG (0.37) | PPARGPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103554006-A | Use of indole derivatives as nurr-1 activators for the application thereof as a medicament for the treatment of parkinson's disease | FOURNIER LAB SA | 2014-02-05 | — | — | CN | disclosed |