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SCHEMBL279507

SCHEMBL279507

COC(=O)OCc1ccc(N(c2cc(C)c(C)c(C)c2)c2ccc(-c3ccc(N(c4ccc(COC(=O)OC)cc4)c4cc(C)c(C)c(C)c4)c(C)c3)cc2C)cc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 3/20 0.37
▸ ALDH1A1 P00352 3/20 0.37
▸ HPGD P15428 2/20 0.37
▸ SMN1; SMN2 Q16637 2/20 0.37
▸ NPC1 O15118 2/20 0.37
▸ GAA P10253 1/20 0.37
▸ TSHR P16473 1/20 0.37
▸ MAPK1 P28482 1/20 0.37
▸ HSD17B10 Q99714 1/20 0.37
▸ ENPP2 Q13822 1/20 0.32
▸ MAPT P10636 4/20 0.32
▸ KEAP1 Q14145 3/20 0.31
▸ NFE2L2 Q16236 3/20 0.31
▸ HSD17B1 P14061 1/20 0.31
▸ HSD17B2 P37059 1/20 0.31
▸ RAB9A P51151 3/20 0.31
▸ MMP12 P39900 1/20 0.31
▸ KCNH2 Q12809 1/20 0.31
▸ ATM Q13315 1/20 0.31
▸ LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL279030 0.92 ALDH1A1 (0.36) KDM4EALDH1A1HPGDSMN1; SMN2NPC1
SCHEMBL279354 0.81 NPC1 (0.41) ALDH1A1HPGDNPC1ENPP2MAPT
SCHEMBL279187 0.81 MAPT (0.35) ALDH1A1SMN1; SMN2MAPK1MAPTHSD17B1
SCHEMBL14063439 0.80 — —
SCHEMBL14063409 0.80 ALDH1A1 (0.40) KDM4EALDH1A1HPGDSMN1; SMN2NPC1
SCHEMBL14063412 0.79 ALDH1A1 (0.42) KDM4EALDH1A1HPGDSMN1; SMN2NPC1
SCHEMBL279583 0.79 RARB (0.37) ALDH1A1SMN1; SMN2MAPK1MAPTHSD17B1
SCHEMBL279281 0.78 SMN1; SMN2 (0.43) KDM4EALDH1A1HPGDSMN1; SMN2NPC1
SCHEMBL5955193 0.78 CHEK1 (0.36) KCNH2ATM
SCHEMBL279306 0.77 ALDH1A1 (0.51) KDM4EALDH1A1HPGDSMN1; SMN2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8273517-B2 Method of manufacturing electrophotographic photoreceptor, electrophotographic photoreceptor, image-forming apparatus, and process cartridge FUJI XEROX CO., LTD. (JP) 2012-09-25 — — US disclosed
US-8273517-B2 Method of manufacturing electrophotographic photoreceptor, electrophotographic photoreceptor, image-forming apparatus, and process cartridge FUJI XEROX CO., LTD. (JP) 2012-09-25 — — US disclosed
US-8263299-B2 Multilayer; electroconductive support, photosensitive layer of cured phenolic resin having dynamics hardness and elastic deformation; xerography;thin film with few defects;mechanical strength; stability; high quality images FUJI XEROX CO., LTD. (JP) 2012-09-11 — — US disclosed
US-8263299-B2 Multilayer; electroconductive support, photosensitive layer of cured phenolic resin having dynamics hardness and elastic deformation; xerography;thin film with few defects;mechanical strength; stability; high quality images FUJI XEROX CO., LTD. (JP) 2012-09-11 — — US disclosed
US-20120134713-A1 METHOD OF MANUFACTURING ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC PHOTORECEPTOR, IMAGE-FORMING APPARATUS, AND PROCESS CARTRIDGE FUJI XEROX CO., LTD. (JP) 2012-05-31 — — US disclosed
US-20120134713-A1 METHOD OF MANUFACTURING ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC PHOTORECEPTOR, IMAGE-FORMING APPARATUS, AND PROCESS CARTRIDGE FUJI XEROX CO., LTD. (JP) 2012-05-31 — — US disclosed
US-8133645-B2 Method of manufacturing electrophotographic photoreceptor, electrophotographic photoreceptor, image-forming apparatus, and process cartridge FUJI XEROX CO., LTD. (JP) 2012-03-13 — — US disclosed
US-8133645-B2 Method of manufacturing electrophotographic photoreceptor, electrophotographic photoreceptor, image-forming apparatus, and process cartridge FUJI XEROX CO., LTD. (JP) 2012-03-13 — — US disclosed
US-8110328-B2 Conductive support with photosensitive layer containing curable resin, fluorinated surfactants and charge transfer compound FUJI XEROX CO., LTD. (JP) 2012-02-07 — — US disclosed
US-8110328-B2 Conductive support with photosensitive layer containing curable resin, fluorinated surfactants and charge transfer compound FUJI XEROX CO., LTD. (JP) 2012-02-07 — — US disclosed
US-20080299473-A1 METHOD OF MANUFACTURING ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC PHOTORECEPTOR, IMAGE-FORMING APPARATUS, AND PROCESS CARTRIDGE FUJI XEROX CO., LTD. (JP) 2008-12-04 — — US disclosed
US-20080299473-A1 METHOD OF MANUFACTURING ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC PHOTORECEPTOR, IMAGE-FORMING APPARATUS, AND PROCESS CARTRIDGE FUJI XEROX CO., LTD. (JP) 2008-12-04 — — US disclosed
US-20080261135-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE AND IMAGE FORMING APPARATUS FUJI XEROX CO., LTD. (JP) 2008-10-23 — — US disclosed
US-20080261135-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE AND IMAGE FORMING APPARATUS FUJI XEROX CO., LTD. (JP) 2008-10-23 — — US disclosed
US-20080031642-A1 Electrophotographic photoreceptor, image forming apparatus, and process cartridge FUJI XEROX CO., LTD. (JP) 2008-02-07 — — US disclosed
US-20080031642-A1 Electrophotographic photoreceptor, image forming apparatus, and process cartridge FUJI XEROX CO., LTD. (JP) 2008-02-07 — — US disclosed
US-20070065741-A1 Electrophotographic photoreceptor, process cartridge, and image forming apparatus FUJI XEROX CO., LTD. (JP) 2007-03-22 — — US disclosed
US-20070065741-A1 Electrophotographic photoreceptor, process cartridge, and image forming apparatus FUJI XEROX CO., LTD. (JP) 2007-03-22 — — US disclosed
US-20070003850-A1 Curable resin composition, electrophotographic photoreceptor, process cartridge, and image-forming apparatus FUJI XEROX CO., LTD. (JP) 2007-01-04 — — US disclosed
US-20070003850-A1 Curable resin composition, electrophotographic photoreceptor, process cartridge, and image-forming apparatus FUJI XEROX CO., LTD. (JP) 2007-01-04 — — US disclosed