SCHEMBL279528

SCHEMBL279528

C(=Cc1ccc(N(c2ccccc2)c2ccc(C=CC=C(c3ccccc3)c3ccccc3)cc2)cc1)C=C(c1ccccc1)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.39
RELA Q04206 1/20 0.39
ALDH1A1 P00352 3/20 0.39
KDM4E B2RXH2 3/20 0.39
MAOB P27338 1/20 0.39
CYP1A2 P05177 2/20 0.38
CYP2C9 P11712 2/20 0.38
MAPT P10636 2/20 0.38
TDP1 Q9NUW8 2/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2D6 P10635 1/20 0.38
CYP2C19 P33261 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
APP P05067 2/20 0.38
POLB P06746 2/20 0.37
HPGD P15428 1/20 0.36
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
PSMD14 O00487 1/20 0.35
APAF1 O14727 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12284421 1.00 LMNA (0.39) LMNARELAALDH1A1KDM4EMAOB
SCHEMBL6140326 1.00 LMNA (0.39) LMNARELAALDH1A1KDM4EMAOB
SCHEMBL2044135 1.00 LMNA (0.39) LMNARELAALDH1A1KDM4EMAOB
SCHEMBL6140225 1.00 LMNA (0.39) LMNARELAALDH1A1KDM4EMAOB
SCHEMBL6140221 1.00 LMNA (0.39) LMNARELAALDH1A1KDM4EMAOB
SCHEMBL13657502 1.00 LMNA (0.39) LMNARELAALDH1A1KDM4EMAOB
SCHEMBL6140324 1.00 LMNA (0.39) LMNARELAALDH1A1KDM4EMAOB
SCHEMBL8633391 1.00 LMNA (0.39) LMNARELAALDH1A1KDM4EMAOB
SCHEMBL22375346 0.98 RELA (0.42) LMNARELAALDH1A1KDM4EMAOB
SCHEMBL22672072 0.98 RELA (0.42) LMNARELAALDH1A1KDM4EMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 116 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9069268-B2 Polyarylatecarbonate fluoropolymer containing photoconductors XEROX CORPORATION (US) 2015-06-30 US claimed
US-20150079511-A1 POLYARYLATECARBONATE FLUOROPOLYMER CONTAINING PHOTOCONDUCTORS XEROX CORPORATION (US) 2015-03-19 US claimed
EP-2141546-B1 Photoconductors containing Tris and Bis(enylaryl)arylamine XEROX CORP (US) 2013-05-22 EP claimed
US-20120208116-A1 BIS(ENYLARYL)ARYLAMINE CHARGE TRANSPORT LAYER CONTAINING PHOTOCONDUCTORS XEROX CORPORATION (US) 2012-08-16 US claimed
US-7981580-B2 Tris and bis(enylaryl)arylamine mixtures containing photoconductors XEROX CORPORATION (US) 2011-07-19 US claimed
US-7968262-B2 Bis(enylaryl)arylamine containing photoconductors XEROX CORPORATION (US) 2011-06-28 US claimed
US-7745082-B2 Imaging member XEROX CORPORATION (US) 2010-06-29 US claimed
US-20090325092-A1 BIS(ENYLARYL)ARYLAMINE CONTAINING PHOTOCONDUCTORS XEROX CORPORATION (US) 2009-12-31 US claimed
US-20090325095-A1 TRIS AND BIS(ENYLARYL)ARYLAMINE MIXTURES CONTAINING PHOTOCONDUCTORS XEROX CORPORATION (US) 2009-12-31 US claimed
JP-7173112-A None JP disclosed
US-9069268-B2 Polyarylatecarbonate fluoropolymer containing photoconductors XEROX CORPORATION (US) 2015-06-30 US disclosed
US-9069268-B2 Polyarylatecarbonate fluoropolymer containing photoconductors XEROX CORPORATION (US) 2015-06-30 US disclosed
US-9069268-B2 Polyarylatecarbonate fluoropolymer containing photoconductors XEROX CORPORATION (US) 2015-06-30 US disclosed
US-20150079511-A1 POLYARYLATECARBONATE FLUOROPOLYMER CONTAINING PHOTOCONDUCTORS XEROX CORPORATION (US) 2015-03-19 US disclosed
US-7175955-B2 Electrophotographic photoreceptor, electrophotographic process cartridge and image forming apparatus FUJI XEROX CO., LTD. (JP) 2007-02-13 US disclosed
EP-0650956-B1 Triphenylamine derivatives, and charge-transporting materials and electrophotographic photoreceptors containing such derivatives TAKASAGO PERFUMERY CO LTD (JP) 1998-07-15 EP disclosed
US-5573878-A HIGH CHARGING POTENTIALS, HIGH CARRIER MOBILITY TAKASAGO INTERNATIONAL CORPORATION (JP) 1996-11-12 US disclosed
US-5567560-A Triphenylamine derivative charge-transporting material containing electrophotographic photoreceptor TAKASAGO INTERNATIONAL CORPORATION (JP) 1996-10-22 US disclosed
JP-H07173112-A TRIPHENYLAMINE DERIVATIVE, CHARGE TRANSPORT MATERIAL AND ELECTROPHOTOGRAPHIC PHOTORECEPTOR USING THE SAME TAKASAGO INTERNATL CORP 1995-07-11 JP disclosed
EP-0650956-A1 Triphenylamine derivatives, and charge-transporting materials and electrophotographic photoreceptors containing such derivatives Takasago International Corporation (JP) 1995-05-03 EP disclosed