SCHEMBL27952989

SCHEMBL27952989

CC(C)(c1cccc(CC(=O)O)c1)c1cccc(CC(=O)O)c1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 2/20 0.71
CYP1A2 P05177 1/20 0.71
NR1H4 Q96RI1 4/20 0.52
AKR1B1 P15121 1/20 0.52
RXRA P19793 1/20 0.47
RXRB P28702 1/20 0.47
RXRG P48443 1/20 0.47
CYP26A1 O43174 1/20 0.47
CYP26B1 Q9NR63 1/20 0.47
MAPT P10636 3/20 0.45
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
HIF1A Q16665 2/20 0.44
KDM4E B2RXH2 2/20 0.44
HPGD P15428 2/20 0.44
HSD17B10 Q99714 2/20 0.44
LMNA P02545 2/20 0.44
GAA P10253 2/20 0.44
TSHR P16473 2/20 0.44
ESR1 P03372 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL892932 0.89 CYP1A2 (0.71) CYP2C19CYP1A2NR1H4AKR1B1RXRA
SCHEMBL23758511 0.86 CYP1A2 (0.67) CYP2C19CYP1A2NR1H4AKR1B1RXRA
SCHEMBL9004082 0.83 CYP1A2 (1.00) CYP2C19CYP1A2NR1H4AKR1B1RXRA
SCHEMBL9004090 0.83 CYP1A2 (1.00) CYP2C19CYP1A2NR1H4AKR1B1RXRA
SCHEMBL29935522 0.81 MEN1 (0.65) CYP2C19CYP1A2AKR1B1RXRARXRB
SCHEMBL378581 0.81 MEN1 (0.65) CYP2C19CYP1A2AKR1B1RXRARXRB
Hydrochloric Acid SCHEMBL2525493 0.80 MEN1 (0.63) CYP2C19CYP1A2RXRARXRBRXRG
SCHEMBL70565 0.80 AKR1B1 (0.71) CYP2C19CYP1A2AKR1B1RXRBMAPT
SCHEMBL11421088 0.79 AKR1B1 (0.59) CYP2C19CYP1A2NR1H4AKR1B1RXRA
SCHEMBL31645995 0.79 CYP1A2 (0.58) CYP2C19CYP1A2NR1H4AKR1B1RXRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104017241-A Oxygen scavenging molecules, articles containing same, and methods of their use CONSTAR INT INC 2014-09-03 CN disclosed
CN-103911000-A Thermoplastic resin composition having excellent surface gloss, reflectance, anti-yellowing property and moldability CHEIL IND INC 2014-07-09 CN disclosed
CN-102884118-B Oxygen scavenging additives for plastic containers GRAHAM PACKAGING CO 2014-03-19 CN disclosed
CN-101688020-B Oxygen scavenging molecules, articles comprising the same, and methods of use thereof CONSTAR INT INC 2014-01-01 CN disclosed