Sugi Predict

Sugi Predict / Compounds / SCHEMBL378581

SCHEMBL378581

SCHEMBL378581

O=C(O)Cc1cccc(C(F)(F)F)c1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 2/20 0.65
▸ KMT2A Q03164 2/20 0.65
▸ MAPT P10636 1/20 0.65
▸ CYP1A2 P05177 1/20 0.61
▸ CYP2C19 P33261 1/20 0.61
▸ ACP3 P15309 1/20 0.57
▸ RXRA P19793 2/20 0.56
▸ RXRB P28702 2/20 0.56
▸ RXRG P48443 2/20 0.56
▸ PSEN1 P49768 1/20 0.55
▸ PSEN2 P49810 1/20 0.55
▸ APH1B Q8WW43 1/20 0.55
▸ NCSTN Q92542 1/20 0.55
▸ APH1A Q96BI3 1/20 0.55
▸ PSENEN Q9NZ42 1/20 0.55
▸ ALDH1A1 P00352 1/20 0.55
▸ HTT P42858 1/20 0.55
▸ NR4A2 P43354 2/20 0.54
▸ FFAR1 O14842 2/20 0.54
▸ FFAR4 Q5NUL3 2/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29935522 1.00 MEN1 (0.65) MEN1KMT2AMAPTCYP1A2CYP2C19
Hydrochloric Acid SCHEMBL2525493 0.98 MEN1 (0.63) MEN1KMT2AMAPTCYP1A2CYP2C19
Phenylacetic Acid SCHEMBL1807174 0.96 MEN1 (0.66) MEN1KMT2AMAPTCYP1A2CYP2C19
SCHEMBL10441909 0.91 MEN1 (0.56) MEN1KMT2AMAPTCYP1A2CYP2C19
Toluene SCHEMBL28858321 0.91 MEN1 (0.59) MEN1KMT2AMAPTCYP1A2CYP2C19
SCHEMBL23296145 0.90 RXRA (0.58) MEN1KMT2AMAPTCYP1A2CYP2C19
SCHEMBL11665478 0.87 TSHR (0.61) MEN1KMT2AMAPTCYP1A2CYP2C19
SCHEMBL6865758 0.87 MEN1 (0.62) MEN1KMT2AMAPTACP3ALDH1A1
SCHEMBL29213956 0.86 MEN1 (0.62) MEN1KMT2AMAPTACP3ALDH1A1
SCHEMBL31645995 0.86 CYP1A2 (0.58) MEN1KMT2AMAPTCYP1A2CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1486 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4293009-B1 FENFLURAMINE COMPOSITIONS AND METHODS OF PREPARING THE SAME ZOGENIX INTERNATIONAL LTD (GB) 2025-06-11 — — EP claimed
CN-119977814-A Compound AX-Bn with metabolic activity improving function and preparation method thereof 生命奇观(苏州)生物科技有限公司 2025-05-13 — — CN claimed
CN-222240212-U Hydrolysis device for preparing 3-trifluoromethyl phenylacetic acid 大连金点生物科技有限公司 2024-12-27 — — CN claimed
CN-118450782-A Perovskite film and preparation method thereof, HJT-perovskite laminated cell 宣城先进光伏技术有限公司 2024-08-06 — — CN claimed
EP-4293009-A2 FENFLURAMINE COMPOSITIONS AND METHODS OF PREPARING THE SAME Zogenix International Limited (GB) 2023-12-20 — — EP claimed
US-11634377-B2 Fenfluramine compositions and methods of preparing the same ZOGENIX INTERNATIONAL LIMITED (GB) 2023-04-25 — — US claimed
CN-110041206-B Preparation method of cinacalcet impurity 梯尔希（南京）药物研发有限公司 2021-10-19 — — CN claimed
CN-113499330-A Fenfluramine composition and preparation method thereof 周格尼克斯国际有限公司 2021-10-15 — — CN claimed
CN-108883399-B Fenfluramine composition and preparation method thereof 周格尼克斯国际有限公司 2021-06-22 — — CN claimed
US-20210147335-A1 FENFLURAMINE COMPOSITIONS AND METHODS OF PREPARING THE SAME ZOGENIX INTERNATIONAL LIMITED (GB) 2021-05-20 — — US claimed
US-7311767-B2 Forming a salt of a liquid phase change ink carrier of stearyl stearamide, an amine substituted Xanthene, acridine, anthracene or thioxanthene chromogen, and a metal salt capable of forming a compound with two chromogens XEROX CORPORATION (US) 2007-12-25 — — US claimed
CN-101058562-A 3-substituted oxypyridazine derivative with weeding activity and preparation method thereof UNIV NANKAI (CN) 2007-10-24 — — CN claimed
CN-101058563-A 3-substituted amidopyridazine derivative with weeding activity and preparation method thereof UNIV NANKAI (CN) 2007-10-24 — — CN claimed
US-7264951-B1 Enhanced production of taxol and taxanes by cell cultures of Taxus species PHYTON, INC. (US) 2007-09-04 — — US claimed
US-20060021546-A1 Processes for preparing phase change inks XEROX CORPORATION 2006-02-02 — — US claimed
US-20060020141-A1 Metallized dye XEROX CORPORATION 2006-01-26 — — US claimed
US-20060016369-A1 PHASE CHANGE INKS XEROX CORPORATION 2006-01-26 — — US claimed
US-6946025-B2 Process for preparing tetra-amide compounds XEROX CORPORATION (US) 2005-09-20 — — US claimed
US-20050090690-A1 Process for preparing tetra-amide compounds XEROX CORPORATION 2005-04-28 — — US claimed
US-4268687-A Method of making methyl and ethyl esters of (3-trifluoromethylphenyl)-acetic acid HOOKER CHEMICALS & PLASTICS CORP. (US) 1981-05-19 — — US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210147335-A1 FENFLURAMINE COMPOSITIONS AND METHODS OF PREPARING THE SAME FAAH, FAAH2, TPH1 MEN1 2032/4885KMT2A 1462/4885MAPT 4001/4885
US-11634377-B2 Fenfluramine compositions and methods of preparing the same FAAH, FAAH2, TPH1 MEN1 2032/4885KMT2A 1462/4885MAPT 4001/4885
US-20060020141-A1 Metallized dye CDYL, CDY1; CDY1B, CDYL2 MEN1 685/4885KMT2A 1624/4885MAPT 4074/4885
US-20050090690-A1 Process for preparing tetra-amide compounds TAF9, TAF5, TAF1 MEN1 1466/4885KMT2A 826/4885MAPT 539/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.