SCHEMBL29935522

SCHEMBL29935522

O=C(O)Cc1cccc(C(F)(F)F)c1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.65
KMT2A Q03164 2/20 0.65
MAPT P10636 1/20 0.65
CYP1A2 P05177 1/20 0.61
CYP2C19 P33261 1/20 0.61
ACP3 P15309 1/20 0.57
RXRA P19793 2/20 0.56
RXRB P28702 2/20 0.56
RXRG P48443 2/20 0.56
PSEN1 P49768 1/20 0.55
PSEN2 P49810 1/20 0.55
APH1B Q8WW43 1/20 0.55
NCSTN Q92542 1/20 0.55
APH1A Q96BI3 1/20 0.55
PSENEN Q9NZ42 1/20 0.55
ALDH1A1 P00352 1/20 0.55
HTT P42858 1/20 0.55
NR4A2 P43354 2/20 0.54
FFAR1 O14842 2/20 0.54
FFAR4 Q5NUL3 2/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL378581 1.00 MEN1 (0.65) MEN1KMT2AMAPTCYP1A2CYP2C19
Hydrochloric Acid SCHEMBL2525493 0.98 MEN1 (0.63) MEN1KMT2AMAPTCYP1A2CYP2C19
Phenylacetic Acid SCHEMBL1807174 0.96 MEN1 (0.66) MEN1KMT2AMAPTCYP1A2CYP2C19
SCHEMBL10441909 0.91 MEN1 (0.56) MEN1KMT2AMAPTCYP1A2CYP2C19
Toluene SCHEMBL28858321 0.91 MEN1 (0.59) MEN1KMT2AMAPTCYP1A2CYP2C19
SCHEMBL23296145 0.90 RXRA (0.58) MEN1KMT2AMAPTCYP1A2CYP2C19
SCHEMBL11665478 0.87 TSHR (0.61) MEN1KMT2AMAPTCYP1A2CYP2C19
SCHEMBL6865758 0.87 MEN1 (0.62) MEN1KMT2AMAPTACP3ALDH1A1
SCHEMBL29213956 0.86 MEN1 (0.62) MEN1KMT2AMAPTACP3ALDH1A1
SCHEMBL31645995 0.86 CYP1A2 (0.58) MEN1KMT2AMAPTCYP1A2CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025242872-A1 1H-PYRAZOLO[4,3-D]PYRIMIDINE DERIVATIVES Apollo AP45 Limited (GB) 2025-11-27 WO disclosed
EP-4073242-A1 COMPOSITIONS AND METHODS FOR POTENTIATING IMMUNE ACTIVITY Kumquat Biosciences Inc. (US) 2022-10-19 EP disclosed