Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.56 |
| ▸ | TSHR | P16473 | 5/20 | 0.56 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.50 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
| ▸ | ALPL | P05186 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | ATM | Q13315 | 2/20 | 0.48 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphine SCHEMBL29018216 | 1.00 | ALDH1A1 (0.56) | ALDH1A1HSD17B10TSHRCYP2A6TDP1 | |
| Phosphine SCHEMBL1820375 | 1.00 | ALDH1A1 (0.56) | ALDH1A1HSD17B10TSHRCYP2A6TDP1 | |
| Phosphine SCHEMBL9249650 | 0.97 | ALDH1A1 (0.53) | ALDH1A1HSD17B10TSHRCYP2A6TDP1 | |
| SCHEMBL25302086 | 0.97 | ALDH1A1 (0.59) | ALDH1A1HSD17B10TSHRCYP2A6TDP1 | |
| SCHEMBL27953 | 0.97 | ALDH1A1 (0.59) | ALDH1A1HSD17B10TSHRCYP2A6TDP1 | |
| SCHEMBL29350007 | 0.97 | ALDH1A1 (0.59) | ALDH1A1HSD17B10TSHRCYP2A6TDP1 | |
| SCHEMBL17836548 | 0.94 | ALDH1A1 (0.56) | ALDH1A1HSD17B10TSHRCYP2A6TDP1 | |
| Hydrochloric Acid SCHEMBL4268575 | 0.94 | ALDH1A1 (0.56) | ALDH1A1HSD17B10TSHRCYP2A6TDP1 | |
| Ammonia Solution, Strong SCHEMBL3156160 | 0.94 | ALDH1A1 (0.56) | ALDH1A1HSD17B10TSHRCYP2A6TDP1 | |
| SCHEMBL6077039 | 0.94 | ALDH1A1 (0.56) | ALDH1A1HSD17B10TSHRCYP2A6TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115340572-A | Diphosphine ligand containing xanthene skeleton and synthesis and application thereof | 南方科技大学 | 2022-11-15 | — | — | CN | claimed |
| CN-122080424-A | Tetraphenyl ethylene chiral metal cage complex based on chiral Pt metal coordination and preparation method and application thereof | — | 2026-05-26 | — | — | CN | disclosed |
| CN-117693430-A | Compound, rubber blend comprising the compound, vehicle tyre comprising the rubber blend in at least one component, method for producing the compound and use of the compound as an ageing protectant and/or antiozonant and/or dye | 大陆轮胎德国有限公司 | 2024-03-12 | — | — | CN | disclosed |
| CN-116947925-A | Bridged biphenyl monophosphine ligand containing benzofuran structure, and preparation method and application thereof | 中山大学 | 2023-10-27 | — | — | CN | disclosed |
| CN-115340572-B | Biphosphine ligand containing xanthene skeleton and synthesis and application thereof | 南方科技大学 | 2023-05-09 | — | — | CN | disclosed |
| CN-109438205-B | Synthesis method of 2-methyl-2, 3-diaryl propionaldehyde derivative | 西北大学 | 2021-11-12 | — | — | CN | disclosed |
| EP-1136475-B1 | Piperidine and piperazine compounds for use in the treatment of Alzheimer | HOFFMANN LA ROCHE (CH) | 2004-08-18 | — | — | EP | disclosed |
| US-6605723-B2 | Reacting a protected amino acid ester with a 4-substituted butyric acid derivative, cyclizing the protected intermediate, benzylating and decarboxylating the intermediate, asymmetric hydrogenation using a catalyst | HOFFMAN-LA ROCHE INC. | 2003-08-12 | — | — | US | disclosed |
| EP-0751224-B1 | PROCESS FOR PRODUCING (R)-2-AMINO-1-PHENYLETHANOL OR HALOGENATED DERIVATIVE THEREOF, PROCESS FOR PRODUCING OPTICALLY ACTIVE PHENYLSERINE OR HALOGENATED DERIVATIVE THEREOF, AND NOVEL COMPOUND 3-(3-CHLOROPHENYL)SERINE | DAICEL CHEM (JP) | 2003-01-29 | — | — | EP | disclosed |
| US-20010037026-A1 | Process for the preparation of ethanesul fonyl-piperidine derivatives | EVOTEC INTERNATIONAL GMBH (DE) | 2001-11-01 | — | — | US | disclosed |
| US-5846792-A | Method of producing (R)-2-amino-1-phenylethanol and opticaly active phenylserine and their halogen substituted products using tyrosine decarboxylase | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1998-12-08 | — | — | US | disclosed |
| US-5731175-A | Method of producing (R)-2-amino-1-phenylethanol and optically active phenylserine and their halogen substituted products using microbes | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1998-03-24 | — | — | US | disclosed |
| EP-0544455-B1 | Water-soluble alkali metal sulfonate-substituted binaphthylphosphine transition metal complex and enantioselective hydrogenation method using it | TAKASAGO PERFUMERY CO LTD (JP) | 1997-02-12 | — | — | EP | disclosed |
| EP-0751224-A1 | PROCESS FOR PRODUCING (R)-2-AMINO-1-PHENYLETHANOL OR HALOGENATED DERIVATIVE THEREOF, PROCESS FOR PRODUCING OPTICALLY ACTIVE PHENYLSERINE OR HALOGENATED DERIVATIVE THEREOF, AND NOVEL COMPOUND 3-(3-CHLOROPHENYL)SERINE | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1997-01-02 | — | — | EP | disclosed |
| US-5324861-A | Selective hydrogenation of olefins, ketones, imines | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1994-06-28 | — | — | US | disclosed |
| US-5324861-A | Selective hydrogenation of olefins, ketones, imines | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1994-06-28 | — | — | US | disclosed |
| US-5274146-A | Water-soluble alkali metal sulfonate-substituted binaphthylphosphine transition metal complex and enantioselective hydrogenation method using it | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1993-12-28 | — | — | US | disclosed |
| US-5274146-A | Water-soluble alkali metal sulfonate-substituted binaphthylphosphine transition metal complex and enantioselective hydrogenation method using it | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1993-12-28 | — | — | US | disclosed |
| EP-0544455-A1 | Water-soluble alkali metal sulfonate-substituted binaphthylphosphine transition metal complex and enantioselective hydrogenation method using it | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1993-06-02 | — | — | EP | disclosed |
| EP-0544455-A1 | Water-soluble alkali metal sulfonate-substituted binaphthylphosphine transition metal complex and enantioselective hydrogenation method using it | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1993-06-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010037026-A1 | Process for the preparation of ethanesul fonyl-piperidine derivatives | GRIN1, GRIN3A, GRIN2B | ALDH1A1 1434/4885HSD17B10 4479/4885TSHR 1354/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.