Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 6/20 | 0.48 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 2/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27777529 | 0.92 | SCD (0.47) | SCDALDH1A1PKMKDM4ESMN1; SMN2 | |
| SCHEMBL27756654 | 0.87 | SCD (0.49) | SCDPPARGPPARDPPARA | |
| SCHEMBL27777551 | 0.86 | ALDH1A1 (0.37) | SCDALDH1A1PKMKDM4ESMN1; SMN2 | |
| SCHEMBL27957017 | 0.85 | SCD (0.41) | SCDGRIN1GRIN2BPPARGPPARD | |
| SCHEMBL27756798 | 0.85 | SCD (0.38) | SCDGRIN1GRIN2BALDH1A1RXFP1 | |
| SCHEMBL27777545 | 0.84 | SCD (0.47) | SCDALDH1A1PKMKDM4ESMN1; SMN2 | |
| SCHEMBL27756666 | 0.84 | SCD (0.51) | SCDGRIN1GRIN2BALDH1A1PKM | |
| SCHEMBL28778995 | 0.84 | SCD (0.52) | SCDGRIN1GRIN2BALDH1A1PKM | |
| SCHEMBL27777549 | 0.83 | SCD (0.34) | SCDALDH1A1PKMKDM4ESMN1; SMN2 | |
| SCHEMBL27777547 | 0.83 | SCD (0.48) | SCDALDH1A1PKMKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102007123-B | Heterocyclic inhibitors of stearoyl-CoA desaturase | NOVARTIS AG | 2014-04-30 | — | — | CN | claimed |
| CN-102007123-B | Heterocyclic inhibitors of stearoyl-CoA desaturase | NOVARTIS AG | 2014-04-30 | — | — | CN | disclosed |