Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PROKR1 | Q8TCW9 | 16/20 | 0.46 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16954068 | 0.84 | TAAR1 (0.47) | PROKR1TAAR1 | |
| SCHEMBL22137696 | 0.79 | PROKR1 (0.47) | PROKR1TAAR1 | |
| SCHEMBL22063790 | 0.78 | EPHX2 (0.54) | PROKR1AVPR1A | |
| SCHEMBL5584494 | 0.76 | HTR2C (0.58) | — | |
| SCHEMBL20083410 | 0.76 | TAAR1 (0.45) | PROKR1TAAR1 | |
| SCHEMBL14401199 | 0.75 | STS (0.53) | GAA | |
| SCHEMBL1821499 | 0.73 | GAA (0.51) | PROKR1GAATSHRAGTR1 | |
| SCHEMBL1822952 | 0.71 | PROKR1 (0.46) | PROKR1GAATSHRAGTR1HSD11B1 | |
| SCHEMBL7957634 | 0.71 | ALDH1A1 (0.50) | PROKR1 | |
| SCHEMBL4969638 | 0.69 | OPRL1 (0.47) | GAATSHRAGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104031054-A | Chemokine receptor antagonists and methods of use thereof | MILLENNIUM PHARM INC | 2014-09-10 | — | — | CN | disclosed |
| CN-1585772-B | chemokine receptor antagonists and methods and uses thereof | MILLENNIUM PHARM INC | 2014-06-04 | — | — | CN | disclosed |