SCHEMBL27957751

SCHEMBL27957751

CCC(=O)Oc1cccc2c1C(=O)OC2=O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLM Q9NP87 2/20 0.46
POLK Q9UBT6 2/20 0.46
POLL Q9UGP5 2/20 0.46
POLH Q9Y253 2/20 0.46
DRD1 P21728 1/20 0.42
HTR2A P28223 1/20 0.42
ELANE P08246 2/20 0.42
TYMS P04818 2/20 0.39
ALDH1A1 P00352 3/20 0.38
MAPT P10636 1/20 0.38
KDM4E B2RXH2 3/20 0.38
KMT2A Q03164 2/20 0.38
LMNA P02545 1/20 0.38
GLA P06280 1/20 0.38
GAA P10253 1/20 0.38
HPGD P15428 1/20 0.38
MAPK1 P28482 1/20 0.38
HSD17B10 Q99714 1/20 0.38
ACHE P22303 2/20 0.38
ALOX15 P16050 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6367288 0.82 ELANE (0.55) POLMPOLKPOLLPOLHDRD1
SCHEMBL2176042 0.82 KDM4E (0.50) HTR2ATYMSALDH1A1MAPTKDM4E
SCHEMBL27602059 0.79 ELANE (0.56) POLMPOLKPOLLPOLHHTR2A
SCHEMBL11908091 0.78 ELANE (0.39) POLMPOLKPOLLPOLHHTR2A
SCHEMBL9663235 0.78 TDP1 (0.44) ELANETYMSALDH1A1MAPTKDM4E
SCHEMBL28326979 0.77 ALDH1A1 (0.47) POLMPOLKPOLLPOLHDRD1
SCHEMBL21543800 0.77 TTR (0.46) ALDH1A1MAPTKDM4EKMT2ALMNA
SCHEMBL28292184 0.76 MAPT (0.55) POLMPOLKPOLLPOLHDRD1
SCHEMBL27947898 0.76 TYMS (0.39) POLMPOLKPOLLPOLHHTR2A
SCHEMBL9680641 0.75 TOP1 (0.64) TYMSALDH1A1MAPTKMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105873666-B Composite polyamide membrane with high acid content and low azo content DOW GLOBAL TECHNOLOGIES LLC (US) 2019-11-01 CN disclosed
CN-106457160-B Composite polyamide membrane post-treated with nitrous acid 陶氏环球技术有限责任公司 2019-10-08 CN disclosed
CN-105848759-B Desalting an aqueous mixture containing nanosized particles using a fouling resistant reverse osmosis membrane 陶氏环球技术有限责任公司 2019-04-02 CN disclosed
CN-106170333-B Composite polyamide membrane treated with dihydroxyaryl compound and nitrous acid 陶氏环球技术有限责任公司 2019-02-15 CN disclosed
CN-105873665-B Composite polyamide membrane post-treated with nitrous acid 陶氏环球技术有限责任公司 2019-01-01 CN disclosed
CN-105899284-A high-swelling composite polyamide membrane 陶氏环球技术有限责任公司 2016-08-24 CN disclosed
CN-104039429-B composite polyamide membrane DOW GLOBAL TECHNOLOGIES LLC (US) 2016-05-04 CN disclosed
CN-105377406-A Composite polyamide membrane comprising a trihydrocarbon phosphate DOW GLOBAL TECHNOLOGIES INC 2016-03-02 CN disclosed
CN-104918687-A Composite polyamide membranes made via interfacial polymerization using blends of non-polar solvents DOW GLOBAL TECHNOLOGIES LLC 2015-09-16 CN disclosed
CN-104039429-A Composite polyamide membrane DOW GLOBAL TECHNOLOGIES INC 2014-09-10 CN disclosed