Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 6/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.49 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | XDH | P47989 | 1/20 | 0.46 |
| ▸ | FYN | P06241 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12311682 | 0.84 | MAPT (0.48) | MAPTKDM4ETP53CHEK1NPC1 | |
| SCHEMBL11281002 | 0.84 | NPC1 (0.47) | MAPTKDM4ETP53CHEK1NPC1 | |
| SCHEMBL2324238 | 0.82 | ADORA2A (0.62) | MAPTKDM4ETP53CHEK1NPC1 | |
| SCHEMBL2644510 | 0.81 | MAPT (0.45) | MAPTKDM4ETP53CHEK1NPC1 | |
| SCHEMBL11340045 | 0.80 | ALDH1A1 (0.67) | MAPTKDM4ETP53CHEK1NPC1 | |
| SCHEMBL2645112 | 0.79 | CYP11B2 (0.47) | MAPTKDM4ETP53ALDH1A1GAA | |
| SCHEMBL21061932 | 0.78 | EGFR (0.60) | MAPTKDM4ENPC1KMT2AMEN1 | |
| SCHEMBL2645021 | 0.78 | DYRK1A (0.48) | MAPTKDM4ETP53KMT2AMEN1 | |
| SCHEMBL607853 | 0.76 | MAPT (1.00) | MAPTKDM4ETP53NPC1KMT2A | |
| SCHEMBL2644505 | 0.75 | RPS6KA3 (0.46) | MAPTKDM4ETP53CHEK1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101846893-B | Electrophotographic photoreceptor, process cartridge and image forming apparatus | FUJI XEROX CO LTD | 2014-04-09 | — | — | CN | disclosed |