Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC16A3 | O15427 | 7/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.37 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27794541 | 0.95 | KDM4E (0.42) | SLC16A3KDM4ETSHRFOLH1NR4A2 | |
| SCHEMBL27293125 | 0.83 | RARB (0.53) | TSHRPTPN11 | |
| SCHEMBL27680196 | 0.83 | SLC16A3 (0.44) | SLC16A3KDM4ETSHRFOLH1PTPN11 | |
| SCHEMBL27848001 | 0.83 | RARA (0.45) | SLC16A3KDM4ETSHRFOLH1 | |
| SCHEMBL28206854 | 0.82 | RARB (0.54) | TSHRPTPN11 | |
| SCHEMBL9670437 | 0.82 | SLC16A3 (0.43) | SLC16A3KDM4ETSHRFOLH1 | |
| SCHEMBL28132719 | 0.82 | RARB (0.54) | TSHRPTPN11 | |
| SCHEMBL1356425 | 0.81 | RARB (0.51) | TSHRPTPN11 | |
| SCHEMBL9671387 | 0.81 | KDM4E (0.42) | SLC16A3KDM4ETSHRFOLH1 | |
| SCHEMBL3839116 | 0.81 | FOLH1 (0.59) | SLC16A3TSHRFOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103833730-B | Benzo five-membered Azacyclyl piperidine derivative, Its Preparation Method And Use | 沈阳海王生物技术有限公司 | 2017-08-04 | — | — | CN | disclosed |
| CN-103830238-A | Use of benzo five-membered azaheterocyclyl piperidine derivatives | SHENYANG BEIEN PHARMACEUTICAL CO LTD | 2014-06-04 | — | — | CN | disclosed |