Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC16A3 | O15427 | 9/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.38 |
| ▸ | RARB | P10826 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9671387 | 0.93 | KDM4E (0.42) | SLC16A3KDM4ETSHRFOLH1RARB | |
| SCHEMBL9670835 | 0.86 | KDM4E (0.44) | SLC16A3KDM4ETSHRFOLH1 | |
| SCHEMBL27680196 | 0.85 | SLC16A3 (0.44) | SLC16A3KDM4ETSHRFOLH1RARB | |
| SCHEMBL28132719 | 0.84 | RARB (0.54) | TSHRRARB | |
| SCHEMBL28206854 | 0.84 | RARB (0.54) | TSHRRARB | |
| SCHEMBL27960002 | 0.82 | SLC16A3 (0.43) | SLC16A3KDM4ETSHRFOLH1 | |
| SCHEMBL27293125 | 0.82 | RARB (0.53) | TSHRRARB | |
| SCHEMBL27848001 | 0.81 | RARA (0.45) | SLC16A3KDM4ETSHRFOLH1RARB | |
| SCHEMBL28823832 | 0.81 | SLC16A3 (0.46) | SLC16A3TSHR | |
| SCHEMBL1356425 | 0.80 | RARB (0.51) | TSHRRARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5155113-A | Administering 5-fluorouracil and derivatives with pyridine and pyridone derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1992-10-13 | — | — | US | disclosed |
| EP-0180188-B1 | A COMPOSITION FOR INCREASING THE ANTI-CANCER ACTIVITY OF AN ANTI-CANCER COMPOUND | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1992-04-15 | — | — | EP | disclosed |
| EP-0180188-A2 | A composition for increasing the anti-cancer activity of an anti-cancer compound | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1986-05-07 | — | — | EP | disclosed |