Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 8/20 | 0.59 |
| ▸ | BCHE | P06276 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.50 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.50 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.50 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.50 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.50 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.50 |
| ▸ | CACNG3 | O60359 | 1/20 | 0.50 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.50 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | APP | P05067 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | FABP1 | P07148 | 1/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4879677 | 1.00 | ACHE (0.59) | ACHEBCHEKDM4ECACNB4CACNA1A | |
| SCHEMBL27961346 | 1.00 | ACHE (0.59) | ACHEBCHEKDM4ECACNB4CACNA1A | |
| SCHEMBL27961247 | 0.98 | ACHE (0.56) | ACHEBCHEKDM4ECACNB4CACNA1A | |
| SCHEMBL27961311 | 0.98 | ACHE (0.56) | ACHEBCHEKDM4ECACNB4CACNA1A | |
| SCHEMBL5487150 | 0.95 | ACHE (0.55) | ACHEBCHEKDM4ECACNB4CACNA1A | |
| Oxalic Acid SCHEMBL5945376 | 0.94 | ACHE (0.54) | ACHEBCHEKDM4ECACNB4CACNA1A | |
| SCHEMBL28449689 | 0.91 | ACHE (0.56) | ACHEBCHEKDM4ECACNB4CACNA1A | |
| SCHEMBL31139216 | 0.91 | ACHE (0.56) | ACHEBCHEKDM4ECACNB4CACNA1A | |
| SCHEMBL31139207 | 0.89 | ACHE (0.56) | ACHEBCHEKDM4ECACNB4CACNA1A | |
| SCHEMBL31139194 | 0.84 | ACHE (0.57) | ACHEBCHEKDM4ECACNB4CACNA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103864759-A | Tacrine- nicotinic acid conjugate, preparation method and medical application thereof | UNIV CHINA PHARMA | 2014-06-18 | — | — | CN | disclosed |