SCHEMBL27962109

SCHEMBL27962109

Cc1c(Cl)cc(C(C)(C)C)c(O)c1C(C)(C)C

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 6/20 0.62
CYP2C9 P11712 3/20 0.62
CYP2C19 P33261 3/20 0.62
HIF1A Q16665 2/20 0.62
TP53 P04637 1/20 0.62
CA2 P00918 4/20 0.48
ALDH1A1 P00352 3/20 0.48
POLB P06746 1/20 0.48
TYR P14679 1/20 0.48
CA1 P00915 2/20 0.45
CYP1A2 P05177 2/20 0.44
PTGS1 P23219 2/20 0.41
PTGS2 P35354 2/20 0.41
HSPA5 P11021 1/20 0.40
MAPT P10636 2/20 0.39
ALOX15 P16050 2/20 0.39
HPN P05981 1/20 0.39
SIRT5 Q9NXA8 1/20 0.39
GLRA3 O75311 1/20 0.38
GLRB P48167 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27883056 0.84 SMN1; SMN2 (0.53) SMN1; SMN2CYP2C9CYP2C19HIF1ATP53
SCHEMBL10488673 0.82 SMN1; SMN2 (0.65) SMN1; SMN2CYP2C9CYP2C19HIF1ATP53
SCHEMBL11699334 0.82 SMN1; SMN2 (0.50) SMN1; SMN2CYP2C9CYP2C19HIF1ATP53
SCHEMBL13400274 0.81 SMN1; SMN2 (0.54) SMN1; SMN2CYP2C9CYP2C19HIF1ATP53
SCHEMBL1882430 0.79 SMN1; SMN2 (0.52) SMN1; SMN2CYP2C9CYP2C19HIF1ATP53
SCHEMBL5588058 0.79 SMN1; SMN2 (0.52) SMN1; SMN2CYP2C9CYP2C19HIF1ATP53
SCHEMBL392804 0.79 SMN1; SMN2 (0.52) SMN1; SMN2CYP2C9CYP2C19HIF1ATP53
SCHEMBL30448978 0.79 SMN1; SMN2 (0.52) SMN1; SMN2CYP2C9CYP2C19HIF1ATP53
SCHEMBL3039574 0.78 SMN1; SMN2 (0.59) SMN1; SMN2CYP2C9CYP2C19HIF1ATP53
SCHEMBL70468 0.77 CYP2C19 (1.00) SMN1; SMN2CYP2C9CYP2C19HIF1ATP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103788072-A Sterically hindered phenol and benzotriazol disubstituted ionic liquid and preparation method thereof LANZHOU CHEM PHYS INST 2014-05-14 CN disclosed