Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 4/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | TYR | P14679 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | HPN | P05981 | 1/20 | 0.41 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.41 |
| ▸ | GLRA3 | O75311 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24946528 | 0.83 | SMN1; SMN2 (0.53) | SMN1; SMN2CYP2C9CYP2C19TP53HIF1A | |
| SCHEMBL8167714 | 0.82 | CYP2C9 (0.48) | SMN1; SMN2CYP2C9CYP2C19TP53HIF1A | |
| SCHEMBL27962109 | 0.82 | SMN1; SMN2 (0.62) | SMN1; SMN2CYP2C9CYP2C19TP53HIF1A | |
| SCHEMBL5588058 | 0.81 | SMN1; SMN2 (0.52) | SMN1; SMN2CYP2C9CYP2C19TP53HIF1A | |
| SCHEMBL6232540 | 0.81 | HSD17B10 (0.44) | SMN1; SMN2CYP2C9CYP2C19TP53HIF1A | |
| SCHEMBL28419778 | 0.80 | SMN1; SMN2 (0.37) | SMN1; SMN2CYP2C9CYP2C19TP53HIF1A | |
| SCHEMBL11811918 | 0.77 | CA2 (0.41) | SMN1; SMN2CYP2C9CYP2C19TP53HIF1A | |
| SCHEMBL15173818 | 0.77 | CA2 (0.59) | SMN1; SMN2CYP2C9CYP2C19HIF1ACA2 | |
| SCHEMBL10488673 | 0.75 | SMN1; SMN2 (0.65) | SMN1; SMN2CYP2C9CYP2C19TP53HIF1A | |
| SCHEMBL9149388 | 0.75 | CA2 (0.56) | SMN1; SMN2CYP2C9CYP2C19TP53HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4039587-A | Method of preparing polynuclear, halogenated, aromatic benzyl ethers | DYNAMIT NOBEL AKTIENGESELLSCHAFT (DT) | 1977-08-02 | — | — | US | claimed |
| US-4039587-A | Method of preparing polynuclear, halogenated, aromatic benzyl ethers | DYNAMIT NOBEL AKTIENGESELLSCHAFT (DT) | 1977-08-02 | — | — | US | disclosed |