Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.65 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.65 |
| ▸ | TP53 | P04637 | 1/20 | 0.65 |
| ▸ | CA2 | P00918 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | TYR | P14679 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | HPN | P05981 | 1/20 | 0.41 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.41 |
| ▸ | GLRA3 | O75311 | 1/20 | 0.39 |
| ▸ | GLRB | P48167 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ATP2A2 | P16615 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10618591 | 0.85 | SMN1; SMN2 (0.52) | SMN1; SMN2CYP2C9CYP2C19HIF1ATP53 | |
| SCHEMBL24946528 | 0.83 | SMN1; SMN2 (0.53) | SMN1; SMN2CYP2C9CYP2C19HIF1ATP53 | |
| SCHEMBL27962109 | 0.82 | SMN1; SMN2 (0.62) | SMN1; SMN2CYP2C9CYP2C19HIF1ATP53 | |
| SCHEMBL28063692 | 0.80 | SMN1; SMN2 (0.50) | SMN1; SMN2CYP2C9CYP2C19HIF1ATP53 | |
| SCHEMBL9149388 | 0.80 | CA2 (0.56) | SMN1; SMN2CYP2C9CYP2C19HIF1ATP53 | |
| SCHEMBL3039574 | 0.79 | SMN1; SMN2 (0.59) | SMN1; SMN2CYP2C9CYP2C19HIF1ATP53 | |
| SCHEMBL70468 | 0.79 | CYP2C19 (1.00) | SMN1; SMN2CYP2C9CYP2C19HIF1ATP53 | |
| SCHEMBL9777384 | 0.77 | SMN1; SMN2 (0.47) | SMN1; SMN2CYP2C9CYP2C19HIF1ATP53 | |
| SCHEMBL1457169 | 0.76 | GLRA3 (0.65) | SMN1; SMN2CYP2C9CYP2C19HIF1ATP53 | |
| SCHEMBL1456500 | 0.76 | SMN1; SMN2 (0.56) | SMN1; SMN2CYP2C9CYP2C19HIF1ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4039587-A | Method of preparing polynuclear, halogenated, aromatic benzyl ethers | DYNAMIT NOBEL AKTIENGESELLSCHAFT (DT) | 1977-08-02 | — | — | US | claimed |
| JP-63303941-A | — | — | None | — | — | JP | disclosed |
| JP-63130549-A | — | — | None | — | — | JP | disclosed |
| JP-1207253-A | — | — | None | — | — | JP | disclosed |
| US-20230026611-A1 | ARYL HETEROCYCLIC COMPOUNDS AS Kv1.3 POTASSIUM SHAKER CHANNEL BLOCKERS | D. E. SHAW RESEARCH, LLC | 2023-01-26 | — | — | US | disclosed |
| JP-H01207253-A | PRODUCTION OF 2,4-DICHLORO-3-METHYLPHENOL | SUMITOMO CHEM CO LTD | 1989-08-21 | — | — | JP | disclosed |
| JP-S63303941-A | PRODUCTION OF 2,4-DICHLORO-3-METHYLPHENOL | SUMITOMO CHEM CO LTD | 1988-12-12 | — | — | JP | disclosed |
| JP-S63130549-A | PRODUCTION OF 2,4-DICHLORO-3-METHYLPHENOL | SUMITOMO CHEM CO LTD | 1988-06-02 | — | — | JP | disclosed |
| US-4039587-A | Method of preparing polynuclear, halogenated, aromatic benzyl ethers | DYNAMIT NOBEL AKTIENGESELLSCHAFT (DT) | 1977-08-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230026611-A1 | ARYL HETEROCYCLIC COMPOUNDS AS Kv1.3 POTASSIUM SHAKER CHANNEL BLOCKERS | KCNA3, KCNH2, KCNJ2 | SMN1; SMN2 2503/4885CYP2C9 599/4885CYP2C19 670/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.