Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | HTR2A | P28223 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.49 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.49 |
| ▸ | IDO1 | P14902 | 2/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.49 |
| ▸ | TSPO | P30536 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL490906 | 0.81 | HSD17B10 (0.66) | HSD17B10HTR2AMEN1KMT2AMTNR1A | |
| SCHEMBL6983148 | 0.80 | ALDH1A1 (0.47) | HSD17B10HTR2AMEN1KMT2A | |
| SCHEMBL6203715 | 0.79 | HTR2A (0.63) | HSD17B10HTR2AMEN1KMT2AMTNR1A | |
| SCHEMBL8532221 | 0.78 | HSD17B10 (0.62) | HSD17B10HTR2AMEN1KMT2AMTNR1A | |
| SCHEMBL30861230 | 0.77 | HTR2A (0.65) | HSD17B10HTR2AMEN1KMT2AMTNR1A | |
| SCHEMBL5285095 | 0.77 | HTR2A (0.65) | HSD17B10HTR2AMEN1KMT2AMTNR1A | |
| SCHEMBL3459047 | 0.77 | HTR2A (0.70) | HSD17B10HTR2AIDO1ADRA1ATAAR1 | |
| SCHEMBL13692380 | 0.77 | HTR2A (0.70) | HSD17B10HTR2AIDO1ADRA1ATAAR1 | |
| SCHEMBL4960829 | 0.76 | HTR2A (0.74) | HSD17B10HTR2AIDO1ADRA1ATAAR1 | |
| SCHEMBL490808 | 0.76 | HSD17B10 (0.55) | HSD17B10HTR2AMEN1KMT2AMTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102083821-B | Hepatitis c virus inhibitors | BRISTOL MYERS SQUIBB CO | 2014-09-17 | — | — | CN | disclosed |
| CN-103936819-A | Hepatitis c virus inhibitors | BRISTOL MYERS SQUIBB CO | 2014-07-23 | — | — | CN | disclosed |