Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6983147 | 0.90 | KMT2A (0.55) | ALDH1A1TSHRMEN1KMT2ARAB9A | |
| SCHEMBL27964009 | 0.80 | HSD17B10 (0.58) | HSD17B10HTR2AMEN1KMT2A | |
| SCHEMBL490906 | 0.71 | HSD17B10 (0.66) | HSD17B10HTR2AMEN1KMT2A | |
| SCHEMBL6701768 | 0.71 | POLB (0.50) | ALDH1A1KDM4EMEN1KMT2APTGDR2 | |
| SCHEMBL4113759 | 0.71 | MAPT (0.61) | ALDH1A1KDM4EPTGDR2RAB9A | |
| SCHEMBL10662633 | 0.70 | KMT2A (0.48) | ALDH1A1TSHRHSD17B10MEN1KMT2A | |
| SCHEMBL6203715 | 0.70 | HTR2A (0.63) | ALDH1A1HSD17B10HTR2AMEN1KMT2A | |
| SCHEMBL13979934 | 0.69 | ALDH1A1 (0.48) | ALDH1A1TSHRKDM4EHSD17B10MEN1 | |
| SCHEMBL8532221 | 0.69 | HSD17B10 (0.62) | HSD17B10HTR2AMEN1KMT2A | |
| SCHEMBL6703810 | 0.68 | MAPT (0.48) | ALDH1A1KDM4EMEN1KMT2APTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1345897-A1 | CHEMICAL PROCESS AND NEW INTERMEDIATES | SANOFI-SYNTHELABO (FR) | 2003-09-24 | — | — | EP | disclosed |
| WO-2002044150-A1 | CHEMICAL PROCESS AND NEW INTERMEDIATES | SANOFI-SYNTHELABO (FR) | 2002-06-06 | — | — | WO | disclosed |