Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 10/20 | 0.39 |
| ▸ | CES1 | P23141 | 9/20 | 0.39 |
| ▸ | CES2 | O00748 | 4/20 | 0.39 |
| ▸ | PLA2G6 | O60733 | 1/20 | 0.39 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.39 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | GMNN | O75496 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27964438 | 0.98 | FAAH (0.41) | FAAHCES1CES2PLA2G6LPAR1 | |
| SCHEMBL9108762 | 0.90 | HSD17B10 (0.44) | FAAHCES1CES2PLA2G6HSD17B10 | |
| SCHEMBL9099610 | 0.90 | HSD17B10 (0.44) | FAAHCES1CES2PLA2G6HSD17B10 | |
| SCHEMBL28382941 | 0.90 | HSD17B10 (0.44) | FAAHCES1CES2PLA2G6HSD17B10 | |
| SCHEMBL9110676 | 0.90 | HSD17B10 (0.44) | FAAHCES1CES2PLA2G6HSD17B10 | |
| SCHEMBL8856350 | 0.90 | HSD17B10 (0.44) | FAAHCES1CES2PLA2G6HSD17B10 | |
| SCHEMBL27857718 | 0.89 | FAAH (0.41) | FAAHCES1CES2PLA2G6LPAR1 | |
| SCHEMBL27874467 | 0.89 | FAAH (0.41) | FAAHCES1CES2PLA2G6LPAR1 | |
| SCHEMBL27964181 | 0.88 | FAAH (0.37) | FAAHCES1CES2PLA2G6LPAR1 | |
| SCHEMBL27874395 | 0.87 | CES2 (0.39) | FAAHCES1CES2PLA2G6LPAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102471252-B | Process for producing (fluoroalkylthio) acetic acid ester | SUMITOMO CHEMICAL CO | 2014-07-02 | — | — | CN | disclosed |
| CN-103709079-A | Process for preparation of (fluoroalkylthio)acetic acid esters | MASAJI HIROTA HIROYUKI MIYAZAKI TADAYOSHI ITOH | 2014-04-09 | — | — | CN | disclosed |