Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | PIN1 | Q13526 | 12/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.45 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.45 |
| ▸ | NOS1 | P29475 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1200287 | 0.77 | ALDH1A1 (0.66) | ALDH1A1POLBTDP1MEN1KMT2A | |
| SCHEMBL27335197 | 0.75 | PDE10A (0.56) | ALDH1A1PIN1TDP1MEN1KMT2A | |
| SCHEMBL7699099 | 0.73 | MAPT (0.46) | ALDH1A1TDP1MEN1KMT2AKDM4E | |
| SCHEMBL30878071 | 0.73 | MAPT (0.46) | ALDH1A1TDP1MEN1KMT2AKDM4E | |
| SCHEMBL26616688 | 0.72 | ALDH1A1 (0.44) | ALDH1A1POLBTDP1MEN1KMT2A | |
| SCHEMBL34471419 | 0.72 | MEN1 (0.53) | ALDH1A1POLBTDP1MEN1KMT2A | |
| SCHEMBL8331153 | 0.71 | ALDH1A1 (0.63) | ALDH1A1POLBTDP1MEN1KMT2A | |
| Formaldehyde SCHEMBL27876760 | 0.71 | POLB (0.57) | ALDH1A1POLBTDP1MEN1KMT2A | |
| SCHEMBL2317723 | 0.71 | ALDH1A1 (0.51) | ALDH1A1POLBPIN1TDP1MEN1 | |
| SCHEMBL18624564 | 0.71 | KMT2A (0.53) | ALDH1A1POLBTDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103910688-B | 2-propyl group-4-chloro-quinazoline derivative and its preparation method and application | CHEN CHUNLIN (US) | 2016-05-25 | — | — | CN | disclosed |
| CN-103910688-A | 2-propyl-4-chloroquinazoline derivative, its preparation method thereof and its application thereof | CHUNLIN CHEN | 2014-07-09 | — | — | CN | disclosed |